The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
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Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent isletsChronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolismPer-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretionAdenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretionIncreased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretionMitochondrial signals in glucose-stimulated insulin secretion in the beta cell.Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets.The A2b adenosine receptor modulates glucose homeostasis and obesityAcyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice.Linoleic acid stimulates [Ca2+]i increase in rat pancreatic beta-cells through both membrane receptor- and intracellular metabolite-mediated pathways.Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasisCharacterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.Banting lecture 2011: hyperinsulinemia: cause or consequence?Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet?Mutagenesis of rat acyl-CoA synthetase 4 indicates amino acids that contribute to fatty acid binding.Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets.Rab27a: a new face in beta cell metabolism-secretion coupling.Glucose-sensing mechanisms in pancreatic beta-cells.Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?Metabolome response to glucose in the β-cell line INS-1 832/13.A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogensMonomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets.Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.Fatty acids stimulate insulin secretion from human pancreatic islets at fasting glucose concentrations via mitochondria-dependent and -independent mechanisms.Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretionCharacteristics and mechanisms of hypothalamic neuronal fatty acid sensing.Loss of coupling between calcium influx, energy consumption and insulin secretion associated with development of hyperglycaemia in the UCD-T2DM rat model of type 2 diabetes.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion.Splice variant-dependent regulation of beta-cell sodium-calcium exchange by acyl-coenzyme As.Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression.Glucose stimulation of protein acylation in the pancreatic β-cellCloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme.Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells.Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets.CI-MPR deficiency enhances β-cell susceptibility to palmitate.
P2860
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P2860
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@ast
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@en
type
label
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@ast
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@en
prefLabel
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@ast
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@en
P2093
P356
P1433
P1476
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.
@en
P2093
P304
P356
10.1093/JN/130.2.299S
P407
P433
P577
2000-02-01T00:00:00Z