The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway - Wikidata - awgldk - TriplyDB

The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway

The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway

http://www.wikidata.org/entity/Q36762414

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Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link The mitochondrial unfolded protein response—synchronizing genomes Mitochondrial proteostasis in the control of aging and longevity Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!Mitochondrial stress signaling promotes cellular adaptations Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria.Caenorhabditis elegans pathways that surveil and defend mitochondria.The paradox of mitochondrial dysfunction and extended longevity.Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection The unpredictability of prolonged activation of stress response pathways.A Mutation in Caenorhabditis elegans NDUF-7 Activates the Mitochondrial Stress Response and Prolongs Lifespan via ROS and CED-4 A chemical screen to identify inducers of the mitochondrial unfolded protein response in C. elegans.UPR(mt)-mediated cytoprotection and organismal aging.The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans Dialogue between E. coli free radical pathways and the mitochondria of C. elegans.A screen for protective drugs against delayed hypoxic injury.Metabolism and the UPR(mt).Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.Mitochondrial Proteostatic Collapse Leads to Hypoxic Injury.Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer.Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans.Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells.Searching for the elusive mitochondrial longevity signal in C. elegans.The Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways.The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids Cell biology: The stressful influence of microbes.The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.Life-Span Extension by Axenic Dietary Restriction Is Independent of the Mitochondrial Unfolded Protein Response and Mitohormesis in Caenorhabditis elegans.Theory about the Embryo Cryo-Treatment.Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease.The Aging Mitochondria.Ageing and hypoxia cause protein aggregation in mitochondria.UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication.

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P2860

The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway

http://www.wikidata.org/entity/Q36762414

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2013 nî lūn-bûn

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The mitochondrial unfolded pro ...... tion of the mevalonate pathway

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Christophe Pitot

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Manish Rauthan

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Marc Pilon

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Nataly Aguilera Pradenas

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Parmida Ranji

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P2860

Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism

Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

Regulation of the mevalonate pathway

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

Genome-wide RNAi screening in Caenorhabditis elegans

Protein isoprenylation: the fat of the matter.

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.

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