Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.
about
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerHemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals.Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311.Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.Zscan4 Inhibits Maintenance DNA Methylation to Facilitate Telomere Elongation in Mouse Embryonic Stem Cells.Conformational dynamics of the TTD-PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability.The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.Co-administration of iRGD with peptide HPRP-A1 to improve anticancer activity and membrane penetrability.Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter.DNA-Methylation: Master or Slave of Neural Fate Decisions?An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association.Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance.Developmental Functions of the Dynamic DNA Methylome and Hydroxymethylome in the Mouse and Zebrafish: Similarities and Differences.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward ChromatinChromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1
P2860
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P2860
Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@ast
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@en
type
label
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@ast
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@en
prefLabel
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@ast
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@en
P2093
P2860
P356
P1476
Hemi-methylated DNA opens a cl ...... itate its histone recognition.
@en
P2093
Chunyang Cao
Huirong Yang
Jiaolong Wang
Jiemin Wong
Jingdong Cheng
Mengjie Liu
Qiao Zhang
P2860
P2888
P356
10.1038/NCOMMS11197
P407
P577
2016-04-05T00:00:00Z