Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus.
about
Analysis of RNA binding by the dengue virus NS5 RNA capping enzymeEvolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequencesStructure and functionality in flavivirus NS-proteins: perspectives for drug designUniversal primers that amplify RNA from all three flavivirus subgroupsStructural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus MethyltransferaseRecombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexesReassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 proteintrans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells.The NS5A/NS5 proteins of viruses from three genera of the family flaviviridae are phosphorylated by associated serine/threonine kinasescis- and trans-acting elements in flavivirus RNA replicationDengue virus structural differences that correlate with pathogenesis.trans-Complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replicationMarkers for trans-Golgi membranes and the intermediate compartment localize to induced membranes with distinct replication functions in flavivirus-infected cells.Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterizationA tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient miceDerivation and characterization of a dengue type 1 host range-restricted mutant virus that is attenuated and highly immunogenic in monkeys.Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly.Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.Triaryl pyrazoline compound inhibits flavivirus RNA replication.Blocking of Interferon-Induced Jak-Stat Signaling by Japanese Encephalitis Virus NS5 through a Protein Tyrosine Phosphatase-Mediated MechanismTranslation of the Flavivirus Kunjin NS3 Gene in cis but Not Its RNA Sequence or Secondary Structure Is Essential for Efficient RNA PackagingDe Novo Synthesis of Negative-Strand RNA by Dengue Virus RNA-Dependent RNA Polymerase In Vitro: Nucleotide, Primer, and Template ParametersInteraction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assemblyGenetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulationUltrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structuresBiochemical characterization of a recombinant Japanese encephalitis virus RNA-dependent RNA polymeraseStructural bases for substrate recognition and activity in Meaban virus nucleoside-2′-O-methyltransferaseCompletion of Kunjin virus RNA sequence and recovery of an infectious RNA transcribed from stably cloned full-length cDNAPotential High-Throughput Assay for Screening Inhibitors of West Nile Virus ReplicationCRM1-mediated Nuclear Export of Dengue Virus RNA Polymerase NS5 Modulates Interleukin-8 Induction and Virus ProductionCrystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral ReplicationMKRN1 Induces Degradation of West Nile Virus Capsid Protein by Functioning as an E3 LigaseFocus on flaviviruses: current and future drug targetsCrystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolutionCrystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNAThe global ecology and epidemiology of West Nile virusPrmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase familyPerturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongation
P2860
Q21135003-355F029F-E0FB-442A-9211-B490284767B2Q22064551-AA9F7D8C-2BE1-461F-A5DB-8240DE55EF16Q23011530-C72AD77A-2AD8-411E-B160-868FE0A4AA99Q24286946-13227570-A82A-47FA-B1DA-F26197B5DDE6Q24289239-03E44F7A-C156-4288-B1EB-EFA1F9227588Q24323361-79FDAA50-94ED-4A9A-9551-C0BEE464BBB7Q24804894-B43A8064-8C72-4542-9492-20394A5DE7E8Q27469561-825E5CE0-77B9-4EAD-A0E8-B9E1D3E7BB9FQ27469584-E98F9353-1084-4F0D-849F-D86D031923D9Q27469649-D6BABF1E-86AB-46B2-BD45-F2C6F2D6F897Q27469705-5B26741D-50AC-48D5-9D7B-B3FEB575A358Q27469741-22305446-FCF9-49A7-B79A-AE2A44136721Q27469743-74C25D0D-AF4E-4A06-9607-71544983840DQ27470758-31D96190-019E-4EC0-AF98-014E6E84AB3CQ27470900-5A0AEC18-A2BF-4C8F-97CB-09959E6E40B0Q27472613-67D9740A-9B6B-47D7-9702-F63586F2C3CEQ27472824-8EFCF0E7-FD13-4CB7-9FC7-D36DDB646E75Q27472847-99347D98-490B-4B70-8E12-D62F8A2054BBQ27472910-49F21F65-CF6C-48E3-AF08-9BBF6DC90B55Q27472938-A5FB1F36-FF5F-469C-902E-2F8E3009B6D1Q27473130-92DA06F9-F90F-4BDD-976B-ED9861989DD1Q27473235-41A9F9C1-D920-421F-B655-E7006F0474B1Q27477616-A9E499A0-46D3-42F6-BD9F-912F5DD30A2CQ27477711-904C4FDF-C7E8-44D0-8541-358CBA9E6CF9Q27478442-7221E4A6-A2CD-4E4F-BDB4-6085D471E190Q27480770-80B3BAC8-D7D3-4BD8-A3A3-FAB54A408DC9Q27480850-68639628-D7C5-4981-9CFD-930D3988C8B1Q27480941-02CC063C-5B90-45AE-AFFB-7B5F7F7E3610Q27485168-427ED8FD-C14D-40D5-8A8B-D49F87C2C18FQ27485920-2635A0CD-1C9A-4F9C-9208-96F66B24CFFEQ27487569-517111F1-5654-4FFA-9EB5-883FC8BB94ACQ27488888-3FC77882-D5DD-443D-80E9-88C5C981A017Q27490476-CF11C05F-BA41-4566-8E30-B4458CE56AE5Q27490542-26BC55F0-2072-4B69-A32C-EB585F9B718FQ27490926-5AC3C854-58B6-489D-B0AE-807689021857Q27621159-BFFBAD03-C615-480B-9077-7291F166952FQ27664644-3C77608B-0709-408A-BCAB-2C400E719C62Q28083311-41153399-97E0-47B1-8993-6D4FE4989396Q28142367-98570B18-EEDC-4D5D-A2F5-761984C69EE1Q28651848-6B7318C6-8F67-4100-B11C-7954EA1F2F27
P2860
Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and lambda 2 protein of reovirus.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@ast
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@en
type
label
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@ast
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@en
prefLabel
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@ast
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@en
P1476
Computer-assisted identificati ...... lambda 2 protein of reovirus.
@en
P304
P356
10.1099/0022-1317-74-4-733
P407
P478
74 ( Pt 4)
P577
1993-04-01T00:00:00Z