AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass
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An emerging role for adenosine and its receptors in bone homeostasisMetformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathyInflammation and intracellular metabolism: new targets in OAMetformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen DisposalGhrelin: much more than a hunger hormone.Impaired musculoskeletal response to age and exercise in PPARβ(-/-) diabetic miceAMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5.Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strengthMice lacking AMP-activated protein kinase α1 catalytic subunit have increased bone remodelling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment.IGF-I and IGFBP-2 Stimulate AMPK Activation and Autophagy, Which Are Required for Osteoblast DifferentiationInvolvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts.Genetic deletion of catalytic subunits of AMP-activated protein kinase increases osteoclasts and reduces bone mass in young adult mice.Possible involvement of AMP-activated protein kinase in PGE1-induced synthesis of osteoprotegerin in osteoblasts.Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In VivoAllicin inhibits oxidative stress-induced mitochondrial dysfunction and apoptosis by promoting PI3K/AKT and CREB/ERK signaling in osteoblast cellsThe anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing.Functional differences between AMPK α1 and α2 subunits in osteogenesis, osteoblast-associated induction of osteoclastogenesis, and adipogenesis.Dioxinodehydroeckol Enhances the Differentiation of Osteoblasts by Regulating the Expression of Phospho-Smad1/5/8.Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation.Impact of diabetes and its treatments on skeletal diseases.The Correlation between Osteoporosis Occurrences in Both Schizophrenia and Parkinson's Disease.Key genes associated with osteoporosis revealed by genome wide gene expression analysis.Non-pungent long chain capsaicin-analogs arvanil and olvanil display better anti-invasive activity than capsaicin in human small cell lung cancers.Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity.Bone Cell Bioenergetics and Skeletal Energy Homeostasis.Metformin stimulates osteoprotegerin and reduces RANKL expression in osteoblasts and ovariectomized rats.Effects of Bioactive Compounds on Odontogenic Differentiation and Mineralization.Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitisHuman mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by AMP-activated protein kinase.PPAR agonists stimulate adipogenesis at the expense of osteoblast differentiation while inhibiting osteoclast formation and activity.Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.Molecular signaling mechanisms behind polyphenol-induced bone anabolism.Weak bones in diabetes mellitus - an update on pharmaceutical treatment options.AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.Complex interplay among adiposity, insulin resistance and bone health.Histological evidence that metformin reverses the adverse effects of diabetes on orthodontic tooth movement in rats.Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women.(-)-Epigallocathechin-3-gallate, an AMPK activator, decreases ovariectomy-induced bone loss by suppression of bone resorption.Mechanical Vibration Mitigates the Decrease of Bone Quantity and Bone Quality of Leptin Receptor-Deficient Db/Db Mice by Promoting Bone Formation and Inhibiting Bone Resorption.Efficacy of 1% Metformin Gel in Patients With Moderate and Severe Chronic Periodontitis: A Randomized Controlled Clinical Trial.
P2860
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P2860
AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
AMP-activated protein kinase ( ...... o bone formation and bone mass
@ast
AMP-activated protein kinase ( ...... o bone formation and bone mass
@en
type
label
AMP-activated protein kinase ( ...... o bone formation and bone mass
@ast
AMP-activated protein kinase ( ...... o bone formation and bone mass
@en
prefLabel
AMP-activated protein kinase ( ...... o bone formation and bone mass
@ast
AMP-activated protein kinase ( ...... o bone formation and bone mass
@en
P2093
P2860
P1433
P1476
AMP-activated protein kinase ( ...... o bone formation and bone mass
@en
P2093
P2860
P304
P356
10.1016/J.BONE.2010.04.596
P577
2010-04-24T00:00:00Z