Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome. - Wikidata - awgldk - TriplyDB

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

http://www.wikidata.org/entity/Q36776559

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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery Dissecting the phenotypes of Dravet syndrome by gene deletion Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studies Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism Screening of conventional anticonvulsants in a genetic mouse model of epilepsy.Issues related to development of new antiseizure treatments The relationship between genes affecting the development of epilepsy and approaches to epilepsy therapy.Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome.Early-life febrile seizures worsen adult phenotypes in Scn1a mutants.Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies.Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy.Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome.Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening.Novel and de novo mutations in pediatric refractory epilepsy

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P2860

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

http://www.wikidata.org/entity/Q36776559

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

@ast

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

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type

label

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

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Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

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Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

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Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

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JPET.113.203331

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Journal of Pharmacology and Experimental Therapeutics

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Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

@en

P2093

Alvin R Cho

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Christine S Cheah

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John C Oakley

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Todd Scheuer

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William A Catterall

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P2860

Stiripentol: efficacy and tolerability in children with epilepsy

Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO study group

Early identification of refractory epilepsy

Long-term efficacy and tolerance of stiripentaol in severe myoclonic epilepsy of infancy (Dravet's syndrome)

Severe myoclonic epilepsy in infancy: clinical analysis and relation to SCN1A mutations in a Japanese cohort

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation

The pharmacologic treatment of Dravet syndrome

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215-224

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10.1124/JPET.113.203331

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