Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy
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Voltage-gated sodium channel-associated proteins and alternative mechanisms of inactivation and blockResurgent current of voltage-gated Na(+) channelsThe adverse event profile of lacosamide: a systematic review and meta-analysis of randomized controlled trialsDissecting the phenotypes of Dravet syndrome by gene deletionPathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studiesGenetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndromeThe human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegenerationUnexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome.Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancySudden unexpected death in a mouse model of Dravet syndrome.The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.Effect of Seizures on the Developing Brain and Cognition.Bilirubin augments Ca2+ load of developing bushy neurons by targeting specific subtype of voltage-gated calcium channels.Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique.Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.Large-scale structural alteration of brain in epileptic children with SCN1A mutationDisruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channelsImpaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndromeRole of the axonal initial segment in psychiatric disorders: function, dysfunction, and interventionModulation of neuronal sodium channels by the sea anemone peptide BDS-I.Incomplete inactivation and rapid recovery of voltage-dependent sodium channels during high-frequency firing in cerebellar Purkinje neuronsFunctional properties and differential neuromodulation of Na(v)1.6 channels.FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neuronsCross-species conservation of open-channel block by Na channel β4 peptides reveals structural features required for resurgent Na currentDravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology.Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.Severe Myoclonic Epilepsy in Infancy - Adult Phenotype with Bradykinesia, Hypomimia, and Perseverative Behavior: Report of Five Cases.Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and BalanceNa(V)1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythmsAsynchronous Ca2+ current conducted by voltage-gated Ca2+ (CaV)-2.1 and CaV2.2 channels and its implications for asynchronous neurotransmitter release.Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current.Cognitive Deficits Associated with Nav1.1 Alterations: Involvement of Neuronal Firing Dynamics and OscillationsSpecific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome.Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome.Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.Transcriptional expression of voltage-gated Na⁺ and voltage-independent K⁺ channels in the developing rat superficial dorsal horn.Model systems for studying cellular mechanisms of SCN1A-related epilepsy.Focal Scn1a knockdown induces cognitive impairment without seizures.Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.
P2860
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P2860
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy
description
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Oktober 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/10/10)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/10/10)
@nl
наукова стаття, опублікована в жовтні 2007
@uk
مقالة علمية (نشرت في 10-10-2007)
@ar
name
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@ast
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@en
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@nl
type
label
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@ast
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@en
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@nl
prefLabel
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@ast
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@en
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@nl
P2093
P921
P3181
P1476
Reduced sodium current in Purk ...... myoclonic epilepsy in infancy
@en
P2093
Franck Kalume
Ruth E Westenbroek
Todd Scheuer
William A Catterall
P304
11065-11074
P3181
P356
10.1523/JNEUROSCI.2162-07.2007
P407
P50
P577
2007-10-10T00:00:00Z