Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
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BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groovePrinciples and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsOutcome of a workshop on applications of protein models in biomedical researchHypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Comparative Analyses of Transcriptional Profiles in Mouse Organs Using a Pneumonic Plague Model after Infection with Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant.BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition?Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis.Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivationBlockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.Wild-type and mutant p53 proteins interact with mitochondrial caspase-3Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer.Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.The BCL-2 family reunion.Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis.Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells.Neem oil limonoids induces p53-independent apoptosis and autophagy.Mitochondria in human pluripotent stem cell apoptosis.Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.The p53 family and programmed cell deathThe mitochondrial p53 pathway.Quercetin induces mitochondrial mediated apoptosis and protective autophagy in human glioblastoma U373MG cellsWatching the watcher: regulation of p53 by mitochondriaCytoplasmic functions of the tumour suppressor p53.Mitochondria and energetic depression in cell pathophysiologyPUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.TRIM22-Mediated Apoptosis is Associated with Bak Oligomerization in Monocytes.Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.Many players in BCL-2 family affairs.The cytoplasmic side of p53's oncosuppressive activities.Allosteric modulation of protein oligomerization: an emerging approach to drug design."Licensed to kill": tyrosine dephosphorylation and Bak activation.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xLResistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase.
P2860
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P2860
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@ast
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@en
type
label
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@ast
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@en
prefLabel
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@ast
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@en
P2093
P2860
P356
P1476
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
@en
P2093
Adrian A Canutescu
E Christine Pietsch
Erin Perchiniak
Guoli Wang
Maureen E Murphy
P2860
P304
21294-21304
P356
10.1074/JBC.M710539200
P407
P577
2008-06-04T00:00:00Z