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Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancerReactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumorsStabilising the DNA-binding domain of p53 by rational design of its hydrophobic coreStructural evolution of p53, p63, and p73: Implication for heterotetramer formationThe role of the p53 tumor suppressor in metabolism and diabetesmot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cellsDifferential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell modelMicroarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibitionCSF1 is a novel p53 target gene whose protein product functions in a feed-forward manner to suppress apoptosis and enhance p53-mediated growth arrest.The role of HTS in drug discovery at the University of Michigan.Association of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis.Wnt/β-catenin signaling regulates the proliferation and differentiation of mesenchymal progenitor cells through the p53 pathwayNAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.Histological evidence for skin rejuvenation using a combination of pneumatic energy, broadband light, and growth factor therapy.Impact of targeted therapy on outcome of chronic lymphocytic leukemia patients with relapsed del(17p13.1) karyotype at a single centerTrp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer.The suppression of apoptosis by α-herpesvirus.The origins and evolution of the p53 family of genes.YAP accelerates Aβ(25-35)-induced apoptosis through upregulation of Bax expression by interaction with p73.Activation of p38-MAPK by CXCL4/CXCR3 axis contributes to p53-dependent intestinal apoptosis initiated by 5-fluorouracilCombinational delivery of hydrophobic and hydrophilic anticancer drugs in single nanoemulsions to treat MDR in cancerTracing the protectors path from the germ line to the genome.Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation.Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cells.Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure.Gain of cellular adaptation due to prolonged p53 impairment leads to functional switchover from p53 to p73 during DNA damage in acute myeloid leukemia cellsMolecular profiles of pyramidal neurons in the superior temporal cortex in schizophreniaIdentification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: II. Role of human ZIP9 in testosterone-induced prostate and breast cancer cell apoptosis.BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells.Differential colorectal carcinogenesis: Molecular basis and clinical relevanceA fluorescent-based high-throughput screening assay for small molecules that inhibit the interaction of MdmX with p53.Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice.Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Mitochondrial subversion in cancer.The mitochondrial death pathway: a promising therapeutic target in diseasesMDM2-p53 pathway in hepatocellular carcinoma.Mutant p53: one name, many proteins.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The p53 family and programmed cell death
@en
The p53 family and programmed cell death.
@nl
type
label
The p53 family and programmed cell death
@en
The p53 family and programmed cell death.
@nl
prefLabel
The p53 family and programmed cell death
@en
The p53 family and programmed cell death.
@nl
P2093
P2860
P356
P1433
P1476
The p53 family and programmed cell death
@en
P2093
E C Pietsch
S B McMahon
P2860
P2888
P304
P356
10.1038/ONC.2008.315
P407
P577
2008-10-01T00:00:00Z