CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.
about
Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.Genetic alterations in seborrheic keratoses.The molecular balancing act of p16(INK4a) in cancer and aging.Unexpected reduction of skin tumorigenesis on expression of cyclin-dependent kinase 6 in mouse epidermis.Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis.Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation.PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions.
P2860
Q30501787-56BD368F-3342-4BDD-88E5-9708E93FE774Q33829598-DCC0402D-2F64-4AB0-B5DC-4A03E27AEB27Q34038585-3F1CD26F-E6D6-42E1-9823-98ED70568ADEQ34756149-84A504BF-6CAE-47CF-BF93-CC6E1C53BF46Q34887604-1FCDB0AC-4499-4F8D-A896-5A4CB8AAFDDEQ41614081-52A41354-7733-4122-AF5C-A6E2D2CA498CQ42444812-11FA909C-E509-4FC5-8730-D9FE1F0863B5Q42771899-0DB582B9-8D73-4599-B4EB-BABABD41FC1F
P2860
CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
CDK2 activation in mouse epide ...... affect skin tumor development.
@ast
CDK2 activation in mouse epide ...... affect skin tumor development.
@en
type
label
CDK2 activation in mouse epide ...... affect skin tumor development.
@ast
CDK2 activation in mouse epide ...... affect skin tumor development.
@en
prefLabel
CDK2 activation in mouse epide ...... affect skin tumor development.
@ast
CDK2 activation in mouse epide ...... affect skin tumor development.
@en
P2093
P2860
P1476
CDK2 activation in mouse epide ...... affect skin tumor development
@en
P2093
Adrian M Senderowicz
Claudio J Conti
Everardo Macias
Marcelo L Rodriguez-Puebla
Paula L Miliani de Marval
P2860
P304
P356
10.2353/AJPATH.2008.071124
P407
P577
2008-07-03T00:00:00Z