Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2 - Wikidata - awgldk - TriplyDB

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

http://www.wikidata.org/entity/Q36786810

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Effects of the lifestyle habits in breast cancer transcriptional regulation Involvement of noradrenergic transmission in the PVN on CREB activation, TORC1 levels, and pituitary-adrenal axis activity during morphine withdrawal The CRTC1-SIK1 pathway regulates entrainment of the circadian clock Creb coactivators direct anabolic responses and enhance performance of skeletal muscle Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells The LKB1-AMPK pathway: metabolism and growth control in tumour suppression Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.Activation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylation Glucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytes Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.CREB and the CRTC co-activators: sensors for hormonal and metabolic signals Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells Akt inhibition promotes ABCA1-mediated cholesterol efflux to ApoA-I through suppressing mTORC1.TORC: a new twist on corticotropin-releasing hormone gene expression LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Low-glucose enhances keratocyte-characteristic phenotype from corneal stromal cells in serum-free conditions Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation.The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase Bipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activation The expression and function of histamine H₃ receptors in pancreatic beta cells.The role of oestrogens in the adaptation of islets to insulin resistance.Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB.CRTC2 enhances HBV transcription and replication by inducing PGC1α expression.The role of LKB1 and AMPK in cellular responses to stress and damage.Protein phosphatases in pancreatic islets.TNFα-induced DLK activation contributes to apoptosis in the beta-cell line HIT.Phosphodiesterase-4 inhibition as a therapeutic strategy for metabolic disorders.

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P2860

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

http://www.wikidata.org/entity/Q36786810

description

2008 nî lūn-bûn

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2008年论文

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2008年论文

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2008年论文

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name

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

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Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

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Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

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P1476

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2

@en

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Accalia Fu

http://www.w3.org/2001/XMLSchema#string

Andy Cheuk-Him Ng

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Chantal Depatie

http://www.w3.org/2001/XMLSchema#string

Mufida Al Azzabi

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Robert A Screaton

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P2860

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

TORCs: transducers of regulated CREB activity

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell

Transcriptional regulation by the phosphorylation-dependent factor CREB

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

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phosphorylation

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2481316

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