Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylationSpot 14 protein interacts and co-operates with chicken ovalbumin upstream promoter-transcription factor 1 in the transcription of the L-type pyruvate kinase gene through a specificity protein 1 (Sp1) binding siteGlucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes.Characterization of the neuropilin-1 promoter; gene expression is mediated by the transcription factor Sp1.A novel role of Sp1 and Sp3 in the interferon-gamma -mediated suppression of macrophage lipoprotein lipase gene transcription.Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2Glucose regulation of gene transcription.Multiple E-boxes in the distal promoter of the rat pyruvate carboxylase gene function as a glucose-responsive elementGene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factorsMetabolism and proliferation share common regulatory pathways in cancer cells.Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium.Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription.Specificity protein 1 regulates gene expression related to fatty acid metabolism in goat mammary epithelial cells.Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene.Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humansSp1 is required for glucose-induced transcriptional regulation of mouse vesicular glutamate transporter 2 gene.Transcriptional regulation of fatty acid synthase gene and ATP citrate-lyase gene by Sp1 and Sp3 in rat hepatocytes(1).Sp1 sites mediate activation of the plasminogen activator inhibitor-1 promoter by glucose in vascular smooth muscle cells.Multiple and essential Sp1 binding sites in the promoter for transforming growth factor-beta type I receptor.Transcriptional regulatory regions for expression of the rat fatty acid synthase.Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression.Role of sp transcription factors in the regulation of cancer cell metabolism.Visible light exposure induces VEGF gene expression through activation of retinoic acid receptor-alpha in retinoblastoma Y79 cells.Sp3 represses gene expression via the titration of promoter-specific transcription factors.Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1.Glucose regulates the promoter activity of aldolase A and pyruvate kinase M2 via dephosphorylation of Sp1.cAMP prevents the glucose-mediated stimulation of GLUT2 gene transcription in hepatocytes.Polyunsaturated fatty acids inhibit fatty acid synthase and spot-14-protein gene expression in cultured rat hepatocytes by a peroxidative mechanism.Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c.Nutrient and hormonal regulation of pyruvate kinase gene expression.Regulation of mammalian pyruvate dehydrogenase alpha subunit gene expression by glucose in HepG2 cellsCharacteristics of the intron involvement in the mitogen-induced expression of Zfp-36.Human retinal pigment epithelial cell proliferation by the combined stimulation of hydroquinone and advanced glycation end-products via up-regulation of VEGF gene.Sp1 and Sp3 regulate transcriptional activity of the facilitative glucose transporter isoform-3 gene in mammalian neuroblasts and trophoblasts.
P2860
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P2860
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@ast
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@en
type
label
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@ast
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@en
prefLabel
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@ast
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@en
P2860
P356
P1476
Sp1 mediates glucose activation of the acetyl-CoA carboxylase promoter.
@en
P2860
P304
P356
10.1074/JBC.271.3.1385
P407
P577
1996-01-01T00:00:00Z