Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
about
Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinaseAssociation of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligandDirect association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 betaIdentification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cellsTAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosisThe alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signalingSTAT protein recruitment and activation in c-Kit deletion mutantsSpecific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and VavKit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.Epo regulates erythroid proliferation and differentiation through distinct signaling pathways: implication for erythropoiesis and Friend virus-induced erythroleukemia.C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferationA human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.Recent advances in the understanding of mastocytosis: the role of KIT mutations.Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias.Interspecies molecular chimeras of kit help define the binding site of the stem cell factor.Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders.Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1Direct analysis of the binding of Src-homology 2 domains of phospholipase C to the activated epidermal growth factor receptor.Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit.c-kit(+) cells: the tell-tale heart of cardiac regeneration?A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway.Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.Structural aspects of receptor dimerization. c-kit as an example.Pigmentation and proliferation of human melanocytes and the effects of melanocyte-stimulating hormone and ultraviolet B light.Protein kinase C alpha controls erythropoietin receptor signaling.Phosphatidylinositol 3'-kinase associates with p145c-kit as part of a cell type characteristic multimeric signalling complex.Coexpression of c-kit and stem cell factor in breast cancer results in enhanced sensitivity to members of the EGF family of growth factors.Phosphatidylinositol-3' kinase is not required for mitogenesis or internalization of the Flt3/Flk2 receptor tyrosine kinase.Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways.Comparative genomics of human stem cell factor (SCF).IL-6 blocks a discrete early step in lymphopoiesis.Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase.Phosphatidylinositol 3-kinase and Ca2+ influx dependence for ligand-stimulated internalization of the c-Kit receptor.Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).
P2860
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P2860
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@ast
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@en
type
label
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@ast
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@en
prefLabel
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@ast
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@en
P2093
P2860
P356
P1476
Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase.
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.2.678
P407
P577
1992-01-01T00:00:00Z