Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand
about
The role of c-kit and imatinib mesylate in uveal melanoma.Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosisIdentification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptorActivation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxiscDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF moleculesIdentification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinasesaxl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinaseMutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldismStat1 associates with c-kit and is activated in response to stem cell factorCharacterization of ROS1 cDNA from a human glioblastoma cell lineMolecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell linesp21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating proteinRYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifsMolecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulinInteractions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorcDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptorExpression of KIT receptor tyrosine kinase in endothelial cells of juvenile brain tumorsHuman piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor genec-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldismOne-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probesIdentification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter moleculesImmunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implicationsHER-2/neu and CD117 (c-kit) overexpression in patients with pesticide exposure and extensive stage small cell lung carcinoma (ESSCLC).Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cellsCurrent Stem Cell Biomarkers and Their Functional Mechanisms in Prostate CancerMedical treatment for gastro-entero-pancreatic neuroendocrine tumoursFunctional deregulation of KIT: link to mast cell proliferative diseases and other neoplasmsStructural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinasesStructure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit PromoterA G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad DynamicsDesign and pharmacology of a highly specific dual FMS and KIT kinase inhibitorGermline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosisDevelopmental origin and lineage plasticity of endogenous cardiac stem cellsReceptor tyrosine kinase signaling: regulating neural crest development one phosphate at a timeKit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferationThe complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
P2860
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P2860
Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand
description
1987 nî lūn-bûn
@nan
1987 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@ast
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@en
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@nl
type
label
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@ast
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@en
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@nl
prefLabel
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@ast
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@en
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@nl
P2093
P2860
P3181
P1433
P1476
Human proto-oncogene c-kit: a ...... ase for an unidentified ligand
@en
P2093
J Schlessinger
L Coussens
S Munemitsu
T Yang-Feng
P2860
P304
P3181
P407
P577
1987-11-01T00:00:00Z