Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma
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Gold Nanoparticles in Single-Cell Analysis for Surface Enhanced Raman ScatteringTargeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapySingle cell proteomics in biomedicine: High-dimensional data acquisition, visualization and analysis.Current status and perspectives of patient-derived xenograft models in cancer research.Inactivation of Capicua drives cancer metastasisUnderstanding cell signaling in cancer stem cells for targeted therapy - can phosphoproteomics help to reveal the secrets?Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma.Microchip-based single-cell functional proteomics for biomedical applications.Emerging power of proteomics for delineation of intrinsic tumor subtypes and resistance mechanisms to anti-cancer therapies.Evolutionary scalpels for dissecting tumor ecosystems.Recent progress in single-cell cancer genomics.Revisiting CDK Inhibitors for Treatment of Glioblastoma Multiforme.DNA methylation: an epigenetic mark of cellular memory.Current Advances in Highly Multiplexed Antibody-Based Single-Cell Proteomic Measurements.Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.Next generation sequencing and molecular imaging identify EGFR mutation and amplification in a glioblastoma multiforme patient treated with an EGFR inhibitor: a case report.BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways.Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression.Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma.The PI3K Pathway in Human Disease.Using single-cell multiple omics approaches to resolve tumor heterogeneity.Development of the CNS TAP tool for the selection of precision medicine therapies in neuro-oncology.A Molecular Cascade Modulates MAP1B and Confers Resistance to mTOR Inhibition in Human Glioblastoma.Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.Proteomics and phosphoproteomics in precision medicine: applications and challenges.High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors.Space Invaders: Brain Tumor Exploitation of the Stem Cell Niche.Molecular mechanisms of drug resistance in ovarian cancer.ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.Emerging single-cell technologies for functional proteomics in oncology.The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1.Combined c-Met/Trk inhibition overcomes resistance to CDK4/6 inhibitors in Glioblastoma.
P2860
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P2860
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Single-Cell Phosphoproteomics ...... nation Therapy in Glioblastoma
@en
type
label
Single-Cell Phosphoproteomics ...... nation Therapy in Glioblastoma
@en
prefLabel
Single-Cell Phosphoproteomics ...... nation Therapy in Glioblastoma
@en
P2093
P2860
P1433
P1476
Single-Cell Phosphoproteomics ...... nation Therapy in Glioblastoma
@en
P2093
Beatrice Gini
C David James
Dazy Johnson
Huijun Yang
James R Heath
Ken Herrmann
Kenta Masui
Kiwook Hwang
P2860
P304
P356
10.1016/J.CCELL.2016.03.012
P577
2016-04-01T00:00:00Z