RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
about
The biology of DHX9 and its potential as a therapeutic targetThe RNA helicase A in malignant transformationSuppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Use of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions.Dependence of p53-deficient cells on the DHX9 DExH-box helicase.RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1.Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based MethodRepression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.Tumor cell survival dependence on the DHX9 DExH-box helicaseDHX33 Transcriptionally Controls Genes Involved in the Cell CycleRNA helicase DHX9 may be a therapeutic target in lung cancer and inhibited by enoxacinGenotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Suppression of Transposable Elements in Leukemic Stem Cells.The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomasNol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.Polysome-profiling in small tissue samples.
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P2860
RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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name
RNAi screening uncovers Dhx9 a ...... n an Eμ-myc/Bcl-2 mouse model.
@en
type
label
RNAi screening uncovers Dhx9 a ...... n an Eμ-myc/Bcl-2 mouse model.
@en
prefLabel
RNAi screening uncovers Dhx9 a ...... n an Eμ-myc/Bcl-2 mouse model.
@en
P2093
P2860
P50
P1433
P1476
RNAi screening uncovers Dhx9 a ...... in an Eμ-myc/Bcl-2 mouse model
@en
P2093
Abba Malina
Domenic Di Paola
Frank Grosse
Hengli Tang
John R Mills
Maria Zannis-Hadjopoulos
Scott W Lowe
Teresa Lee
P2860
P304
P356
10.1182/BLOOD-2012-06-434365
P407
P577
2013-02-25T00:00:00Z