about
Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Translation initiation factor eIF4F modifies the dexamethasone response in multiple myelomaProtospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage.Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopeciaStimulators of translation identified during a small molecule screening campaignConditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.Adapting CRISPR/Cas9 for functional genomics screens.RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A.Repurposing CRISPR/Cas9 for in situ functional assays.A modular and flexible ESC-based mouse model of pancreatic cancer.Perturbations of RNA helicases in cancer.Targeting the eIF4A RNA helicase as an anti-neoplastic approach.Synthesis of the antiproliferative agent hippuristanol and its analogues from hydrocortisone via Hg(II)-catalyzed spiroketalization: structure-activity relationship.The von Hippel-Lindau protein pVHL inhibits ribosome biogenesis and protein synthesis.Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic mRNA in vertebrate and invertebrate host cells.The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.Pancreatic tumours escape from translational control through 4E-BP1 loss.Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Jerry Pelletier
@en
Jerry Pelletier
@nl
type
label
Jerry Pelletier
@en
Jerry Pelletier
@nl
prefLabel
Jerry Pelletier
@en
Jerry Pelletier
@nl
P31
P496
0000-0003-1963-6466