Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations.

Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations.

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http://www.wikidata.org/entity/Q36799047
Increased cortical expression of the zinc transporter SLC39A12 suggests a breakdown in zinc cellular homeostasis as part of the pathophysiology of schizophrenia.Evidence for impaired glucose metabolism in the striatum, obtained postmortem, from some subjects with schizophrenia.Diverse Effects on M1 Signaling and Adverse Effect Liability within a Series of M1 Ago-PAMs.Changed gene expression in subjects with schizophrenia and low cortical muscarinic M1 receptors predicts disrupted upstream pathways interacting with that receptor.Higher levels of different muscarinic receptors in the cortex and hippocampus from subjects with Alzheimer's disease.A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity.Relationship between muscarinic M1 receptor binding and cognition in medication-free subjects with psychosis.
P2860

Changes in BQCA Allosteric Modulation of [(3)H]NMS Binding to Human Cortex within Schizophrenia and by Divalent Cations.

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http://www.wikidata.org/entity/Q36799047
description
2015 nî lūn-bûn
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2015年の論文
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Changes in BQCA Allosteric Mod ...... renia and by Divalent Cations.
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type
label
Changes in BQCA Allosteric Mod ...... renia and by Divalent Cations.
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prefLabel
Changes in BQCA Allosteric Mod ...... renia and by Divalent Cations.
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P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Changes in BQCA Allosteric Mod ...... hrenia and by Divalent Cations
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932