Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product.
about
E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activationDDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F functionDP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 proteinIdentification of E-box factor TFE3 as a functional partner for the E2F3 transcription factorFull genome sequence analysis of a novel adenovirus of rhesus macaque origin indicates a new simian adenovirus type and species.Analysis of synthesis, stability, phosphorylation, and interacting polypeptides of the 34-kilodalton product of open reading frame 6 of the early region 4 protein of human adenovirus type 5The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.Induction of the cellular E2F-1 promoter by the adenovirus E4-6/7 protein.The E4-6/7 protein functionally compensates for the loss of E1A expression in adenovirus infectionInduction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.Simian virus 40 small t antigen trans activates the adenovirus E2A promoter by using mechanisms distinct from those used by adenovirus E1A.The C-terminal 70 amino acids of the adenovirus E4-ORF6/7 protein are essential and sufficient for E2F complex formationAdenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosisThe interaction of ICP4 with cell/infected-cell factors and its state of phosphorylation modulate differential recognition of leader sequences in herpes simplex virus DNA.Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein.The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complexAdenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transitionActivation of RNA polymerase III transcription of human Alu repetitive elements by adenovirus type 5: requirement for the E1b 58-kilodalton protein and the products of E4 open reading frames 3 and 6.Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F.Defective synthesis of early region 4 mRNAs during abortive adenovirus infections in monkey cellsRole of E2F transcription factor in E1A-mediated trans activation of cellular genes.Identification of a 60-kilodalton Rb-binding protein, RBP60, that allows the Rb-E2F complex to bind DNA.Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domainsGenetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activityA gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4.Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex.Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repressionInteracting domains of E2F1, DP1, and the adenovirus E4 proteinInterferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells.E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection.A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathwayInteraction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription.Stability of the Sp3-DNA complex is promoter-specific: Sp3 efficiently competes with Sp1 for binding to promoters containing multiple Sp-sites.p21 Disrupts the interaction between cdk2 and the E2F-p130 complex.Identification of a novel downstream binding protein implicated in late-phase-specific activation of the adenovirus major late promotor.E1A-mediated activation of the adenovirus E4 promoter can occur independently of the cellular transcription factor E4FA genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.
P2860
Q24307169-A85F3F8A-B815-4EE5-8458-F3A264840899Q24317344-CD0A57B7-A636-48D8-A6AB-0F268443BE42Q24539067-88218208-2D22-4BA3-86AC-AC45FF682DA8Q24594865-2BACF93E-B4D9-49B1-AFE3-6E573FC8A4F8Q24673143-A87ADE10-328B-47D7-9E30-D90E53E5014EQ30881414-3E83334C-0541-4250-A29C-EC78197C957EQ33641023-82D12A5F-55A7-4248-9CFF-056F165F896BQ33783779-F7B3281D-8605-4D98-8B33-745B75928FD2Q33798343-BD1A42A7-A590-4832-BE4B-D369C820F09DQ33806341-1B2B0013-D9EB-4A9B-8CC6-B421A23B142FQ33825089-A94D9B44-0C28-4D59-B9AA-E90AE0709892Q33933744-69937F56-5E14-4DEE-BD73-59687DE86E7FQ35796608-F225322A-9A78-4894-BF18-8A51DA797402Q35868343-1419BE33-E28F-41AD-A0F0-2D80578CC73DQ35921488-6388A246-834C-4368-B851-AE899C7E090DQ35934834-7AB6F2FD-703E-46DD-A059-47E5695C80FAQ36646716-37CCDBE1-8CE0-4C89-8981-CEBBA676FE87Q36682464-08E6AD23-AC69-4C3E-9EA6-6D96DE587FA3Q36684807-01F9BFEB-ADBC-4AC1-B527-485308ADD9B9Q36689847-7AB67DC6-7458-4E8C-9879-F5479EA9A915Q36697561-088570AA-0317-4313-9BD8-C124B9EB0DCBQ36700904-5566961E-C437-4E95-AB18-86DD82E37F0DQ36702674-912493A4-A760-466C-BA2E-C698CCCD38F5Q36702851-649E859B-521A-452E-81EC-65E9891F3186Q36798136-4D2EA4AC-F378-4525-85C4-34F03E292C31Q36808087-70D89A03-D956-48BE-8E4B-327306BD90BFQ36824394-3C825980-A089-4E10-81F1-F789F3FBB79CQ36828899-9428670D-BBBF-4231-8DA3-4A821AD85CAFQ37112680-968548B9-EB44-4F4E-8DF7-83660349B6E4Q38306445-58C15A7D-1127-475E-9F8E-6E7BE74AA401Q38316694-21BE4ACD-8B72-45DF-BB5C-BA0200DE802AQ38325725-723CB5A0-F7FE-43A6-8FB2-FFAAAC992E95Q38340261-A6A4C2E5-E3F4-425A-9B19-4335E8E2AE48Q39872693-E8F5AB43-1ED7-4049-BF09-434F41E0A7DDQ39922572-E1335461-2AC2-4871-B834-383B8CEB4F67Q40018242-1839DB6F-8C63-4890-91C1-7A3ECBB86660Q40533356-642A5D5D-46F8-467A-9130-B38AE7090207Q40640159-C904FF69-AE4D-4388-A5C9-FFF79387299DQ40656289-56A69BB1-EAD5-48FB-B745-9D09AB87BC12
P2860
Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene product.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Activation of the E2F transcri ...... ediated by an E4 gene product.
@ast
Activation of the E2F transcri ...... ediated by an E4 gene product.
@en
type
label
Activation of the E2F transcri ...... ediated by an E4 gene product.
@ast
Activation of the E2F transcri ...... ediated by an E4 gene product.
@en
prefLabel
Activation of the E2F transcri ...... ediated by an E4 gene product.
@ast
Activation of the E2F transcri ...... ediated by an E4 gene product.
@en
P2093
P2860
P1433
P1476
Activation of the E2F transcri ...... ediated by an E4 gene product.
@en
P2093
J R Nevins
P Raychaudhuri
P2860
P304
P407
P577
1990-06-01T00:00:00Z