Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients.

Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients.

Item
http://www.wikidata.org/entity/Q36807761
Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecanComment on a published paper. The adverse cholinergic effects of the chemotherapeutic agent irinotecan (CPT-11) were unlikely to be mediated by the inhibition of acetylcholinesterase (AChE)Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer.The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours.Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity.Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy.A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer.Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy.Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.Therapeutic targeting of CPT-11 induced diarrhea: a case for prophylaxis.
P2860

Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients.

Item
http://www.wikidata.org/entity/Q36807761
description
1996 nî lūn-bûn
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1996年の論文
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1996年論文
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1996年論文
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1996年論文
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1996年論文
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1996年論文
@zh-tw
1996年论文
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1996年论文
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1996年论文
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name
Identification and properties ...... d from the plasma of patients.
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Identification and properties ...... d from the plasma of patients.
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type
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Identification and properties ...... d from the plasma of patients.
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Identification and properties ...... d from the plasma of patients.
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Identification and properties ...... d from the plasma of patients.
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Identification and properties ...... d from the plasma of patients.
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P1476
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P1433
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Identification and properties ...... d from the plasma of patients.
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P2093
P304
P31
P407
P433
P478
P577
P698