Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.
about
Intrabody and Parkinson's diseaseProlonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neuCrystal structure of the anti-(carcinoembryonic antigen) single-chain Fv antibody MFE-23 and a model for antigen binding based on intermolecular contactsStructural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cellsNovel beta-lactamase-random peptide fusion libraries for phage display selection of cancer cell-targeting agents suitable for enzyme prodrug therapyAn improved phage-display panning method to produce an HM-1 killer toxin anti-idiotypic antibody.Cancer cell-specific internalizing ligands from phage displayed beta-lactamase-peptide fusion libraries.A thousand points of light or just dim bulbs? Radiolabeled antibodies and colorectal cancer imaging.Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids.Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by FluorescenceNanoscale strategies: treatment for peripheral vascular disease and critical limb ischemia.Radionuclides in the investigation of the urinary tract.Generation and Characterization of an scFv Directed against Site II of Rabies Glycoprotein.Antibody constructs for radioimmunodiagnosis and treatment of human pancreatic cancer.New approaches to antibody therapy.Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applicationsThe multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategiesMonoclonal antibodies for brain tumour treatment.Antigen specificity and tumour targeting efficiency of a human carcinoembryonic antigen-specific scFv and affinity-matured derivativesHigh-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.Immunoscreening protocols for the identification of clinically useful antibodies and antigens.Tailoring antibodies for radionuclide delivery.Development of antibodies for cancer therapy.Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.Radionuclide-Based Cancer Imaging Targeting the Carcinoembryonic Antigen.Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sitesPreclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors.Immune therapies for neuroblastoma.Anti-GD2 antibody therapy for GD2-expressing tumors.Nanoparticles: a promising modality in the treatment of sarcomas.Tumour targeting of humanised cross-linked divalent-Fab' antibody fragments: a clinical phase I/II studyT lymphocytes isolated from patients with advanced colorectal cancer are suitable for gene immunotherapy approaches.Stem Cell Smart Technology, where are we now and how far we have to go?Definition and application of good manufacturing process-compliant production of CEA-specific chimeric antigen receptor expressing T-cells for phase I/II clinical trial.Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus.Construction of di-scFv through a trivalent alkyne-azide 1,3-dipolar cycloaddition.Human monocytes expressing a CEA-specific chimeric CD64 receptor specifically target CEA-expressing tumour cells in vitro and in vivo.The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicityProfessor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.
P2860
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P2860
Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Clinical evidence of efficient ...... from a combinatorial library.
@ast
Clinical evidence of efficient ...... from a combinatorial library.
@en
type
label
Clinical evidence of efficient ...... from a combinatorial library.
@ast
Clinical evidence of efficient ...... from a combinatorial library.
@en
prefLabel
Clinical evidence of efficient ...... from a combinatorial library.
@ast
Clinical evidence of efficient ...... from a combinatorial library.
@en
P2093
P2860
P356
P1433
P1476
Clinical evidence of efficient ...... from a combinatorial library.
@en
P2093
Chester KA
Hawkins RE
Hope-Stone LD
Johnson CJ
P2860
P2888
P304
P356
10.1038/NM0996-979
P407
P577
1996-09-01T00:00:00Z