A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation
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Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationMicroRNA networks regulate development of brown adipocytesA-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activationTGF-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of p38MAPK pathwayCdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathwayOcular abnormalities in mice lacking the immunoglobulin superfamily member CdoN-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblastsAbl promotes cadherin-dependent adhesion and signaling in myoblasts.SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation.KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation.Bmcc1s, a novel brain-isoform of Bmcc1, affects cell morphology by regulating MAP6/STOP functions.p38-{gamma}-dependent gene silencing restricts entry into the myogenic differentiation program.Transforming growth factor-beta-activated kinase 1 is an essential regulator of myogenic differentiation.p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice.Cdo interacts with APPL1 and activates Akt in myoblast differentiation.The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain.Regulation of promyogenic signal transduction by cell-cell contact and adhesion.Mir193b-365 is essential for brown fat differentiation.Cross-species analyses identify the BNIP-2 and Cdc42GAP homology (BCH) domain as a distinct functional subclass of the CRAL_TRIO/Sec14 superfamilyTRAF6 promotes myogenic differentiation via the TAK1/p38 mitogen-activated protein kinase and Akt pathways.Regulation of myogenic activation of p38 MAPK by TACE-mediated TNFα releaseCDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signalingEphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell linesImportance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B.Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation.Regulation of myotube formation by the actin-binding factor drebrin.Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo-activated ERK1/2 is critical for the promyogenic function of Stim1Syntaxin 4 regulates the surface localization of a promyogenic receptor Cdo thereby promoting myogenic differentiation.Cdo Regulates Surface Expression of Kir2.1 K+ Channel in Myoblast DifferentiationSmooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo.Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A.Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation.Heparin-binding EGF-like growth factor and miR-1192 exert opposite effect on Runx2-induced osteogenic differentiation.Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro.PKN2 and Cdo interact to activate AKT and promote myoblast differentiation.The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis.How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members?Functional plasticity of the BNIP-2 and Cdc42GAP Homology (BCH) domain in cell signaling and cell dynamics.Signaling mechanisms in mammalian myoblast fusion.Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro.
P2860
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P2860
A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@ast
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@en
type
label
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@ast
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@en
prefLabel
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@ast
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@en
P2093
P2860
P356
P1476
A Cdo-Bnip-2-Cdc42 signaling p ...... y and myogenic differentiation
@en
P2093
Giichi Takaesu
Gyu-Un Bae
Jong-Sun Kang
Min-Jeong Yi
Robert S Krauss
Yi Ting Zhou
Youn-Joo Yang
P2860
P304
P356
10.1083/JCB.200801119
P407
P577
2008-08-04T00:00:00Z