The role of transcriptional activator GATA-1 at human beta-globin HS2 - Wikidata - awgldk - TriplyDB

The role of transcriptional activator GATA-1 at human beta-globin HS2

The role of transcriptional activator GATA-1 at human beta-globin HS2

http://www.wikidata.org/entity/Q36824044

about

The GATA1-HS2 enhancer allows persistent and position-independent expression of a β-globin transgene An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes.Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus.A novel regulatory element (E77) isolated from CHO-K1 genomic DNA enhances stable gene expression in Chinese hamster ovary cells Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci.The hematopoietic regulator TAL1 is required for chromatin looping between the β-globin LCR and human γ-globin genes to activate transcription.Enhancer requirement for histone methylation linked with gene activation.The intrinsic genetic and epigenetic regulator factors as therapeutic targets, and the effect on fetal globin gene expression.Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis.

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The role of transcriptional activator GATA-1 at human beta-globin HS2

http://www.wikidata.org/entity/Q36824044

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

The role of transcriptional activator GATA-1 at human beta-globin HS2

@en

type

label

The role of transcriptional activator GATA-1 at human beta-globin HS2

@en

prefLabel

The role of transcriptional activator GATA-1 at human beta-globin HS2

@en

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Nucleic Acids Research

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The role of transcriptional activator GATA-1 at human beta-globin HS2

@en

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AeRi Kim

http://www.w3.org/2001/XMLSchema#string

Ann Dean

http://www.w3.org/2001/XMLSchema#string

Chul Geun Kim

http://www.w3.org/2001/XMLSchema#string

Jong Joo Lee

http://www.w3.org/2001/XMLSchema#string

Narae Choi

http://www.w3.org/2001/XMLSchema#string

Sang-Hyun Song

http://www.w3.org/2001/XMLSchema#string

Youngran Cho

http://www.w3.org/2001/XMLSchema#string

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Locus control regions

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.

Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro

Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

GATA1 function, a paradigm for transcription factors in hematopoiesis

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4521-4528

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scholarly article

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10.1093/NAR/GKN368

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14

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36

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2008-06-27T00:00:00Z

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5268776

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18586828

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2504316

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