Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli
about
Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstructionPoint mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response.Population structure of gut Escherichia coli and its role in development of extra-intestinal infections.High-resolution two-locus clonal typing of extraintestinal pathogenic Escherichia coli.Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosidesCombinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice.Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection.Treatment and prevention of urinary tract infection with orally active FimH inhibitors.Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding.Single clinical isolates from acute uncomplicated urinary tract infections are representative of dominant in situ populations.Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization.An Environmental Shiga Toxin-Producing Escherichia coli O145 Clonal Population Exhibits High-Level Phenotypic Variation That Includes Virulence TraitsAdaptation of Escherichia coli traversing from the faecal environment to the urinary tract.Population variability of the FimH type 1 fimbrial adhesin in Klebsiella pneumoniae.Conditional Function of Autoaggregative Protein Cah and Common cah Mutations in Shiga Toxin-Producing Escherichia coli.Conflict of interests: multiple signal peptides with diverging goals.
P2860
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P2860
Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Adaptive mutations in the sign ...... uropathogenic Escherichia coli
@en
type
label
Adaptive mutations in the sign ...... uropathogenic Escherichia coli
@en
prefLabel
Adaptive mutations in the sign ...... uropathogenic Escherichia coli
@en
P2093
P2860
P356
P1476
Adaptive mutations in the sign ...... uropathogenic Escherichia coli
@en
P2093
Evgeni V Sokurenko
Leah S Ronald
Nina Yazvenko
Olga Yakovenko
Pavel Aprikian
Sujay Chattopadhyay
P2860
P304
10937-10942
P356
10.1073/PNAS.0803158105
P407
P50
P577
2008-07-29T00:00:00Z