Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. - Wikidata - awgldk - TriplyDB

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding.

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding.

http://www.wikidata.org/entity/Q37478977

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Adhesive Pili in UTI Pathogenesis and Drug Development Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection Escherichia coli physiology and metabolism dictates adaptation to diverse host microenvironments Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili Structure-Based Drug Design and Optimization of Mannoside Bacterial FimH Antagonists Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.Sensing and adhesion are adaptive functions in the plant pathogenic xanthomonads.Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli.Aberrant community architecture and attenuated persistence of uropathogenic Escherichia coli in the absence of individual IHF subunits.Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response.Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice.Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection.Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection.Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli.Surface Plasmon Resonance (SPR) for the Evaluation of Shear-Force-Dependent Bacterial Adhesion.Microevolution in fimH gene of mucosa-associated Escherichia coli strains isolated from pediatric patients with inflammatory bowel disease Metabolism and Fitness of Urinary Tract Pathogens.A set of powerful negative selection systems for unmodified Enterobacteriaceae.Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice.Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection.Structure, Function, and Assembly of Adhesive Organelles by Uropathogenic Bacteria The ST131 Escherichia coli H22 subclone from human intestinal microbiota: Comparison of genomic and phenotypic traits with those of the globally successful H30 subclone Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific.Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli.Application and Optimization of relE as a Negative Selection Marker for Making Definitive Genetic Constructs in Uropathogenic Escherichia coli A central metabolic circuit controlled by QseC in pathogenic Escherichia coli.Comprehensive mutagenesis of the fimS promoter regulatory switch reveals novel regulation of type 1 pili in uropathogenic Escherichia coli.A tale of two pili: assembly and function of pili in bacteria.Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection.Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era.Androgens Enhance Male Urinary Tract Infection Severity in a New Model Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections.Treatment and prevention of urinary tract infection with orally active FimH inhibitors.Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation.

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Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding.

http://www.wikidata.org/entity/Q37478977

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 December 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Positive selection identifies ...... n addition to mannose binding.

@en

Positive selection identifies ...... n addition to mannose binding.

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type

label

Positive selection identifies ...... n addition to mannose binding.

@en

Positive selection identifies ...... n addition to mannose binding.

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prefLabel

Positive selection identifies ...... n addition to mannose binding.

@en

Positive selection identifies ...... n addition to mannose binding.

@nl

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PNAS.0902179106

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Proceedings of the National Academy of Sciences of the United States of America

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Positive selection identifies ...... in addition to mannose binding

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Chia S Hung

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Corinne K Cusumano

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Jennifer N Walker

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Jerome S Pinkner

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Julie Bouckaert

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Scott J Hultgren

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Zhaoli Li

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P2860

Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract

Environmental regulation of the fim switch controlling type 1 fimbrial phase variation in Escherichia coli K-12: effects of temperature and media

Structural basis of chaperone function and pilus biogenesis

Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection

Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation

FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria

Differential stability and trade-off effects of pathoadaptive mutations in the Escherichia coli FimH adhesin

Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis.

Phylogenomic analysis of natural selection pressure in Streptococcus genomes.

Detection of intracellular bacterial communities in human urinary tract infection.

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22439-22444

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scholarly article

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10.1073/PNAS.0902179106

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52

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106

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Jeffrey I. Gordon

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2009-12-16T00:00:00Z

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40696117

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20018753

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2794649

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