The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging.
about
The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degenerationRole of signal transduction crosstalk between adenylyl cyclase and MAP kinase in hippocampus-dependent memoryDevelopment and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's diseaseNeuroprotective and neuroregenerative effects of nimodipine in a model system of neuronal differentiation and neurite outgrowth.Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neuronsCalcium overload is associated with lipofuscin formation in human retinal pigment epithelial cells fed with photoreceptor outer segmentsSome commonly used brominated flame retardants cause Ca2+-ATPase inhibition, beta-amyloid peptide release and apoptosis in SH-SY5Y neuronal cells.Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.Evidence supporting a role for the calcium-sensing receptor in Alzheimer disease.The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency.Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity.A degenerative retinal process in HIV-associated non-infectious retinopathyReversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged miceCalcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes.Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca(2+) in Neurons and Astroglia.Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: relationships to age-related memory impairments.Altered calcium metabolism in aging CA1 hippocampal pyramidal neuronsAdvancing age alters the contribution of calcium release from smooth endoplasmic reticulum stores in superior cervical ganglion cellsA 10-year follow-up study of the association between calcium channel blocker use and the risk of dementia in elderly hypertensive patientsHippocampal calcium dysregulation at the nexus of diabetes and brain aging.Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease.Learning to learn - intrinsic plasticity as a metaplasticity mechanism for memory formation.Calcium signalling and ER stress in insulin resistance and atherosclerosis.Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice.Enhanced calcium buffering in F344 rat cholinergic basal forebrain neurons is associated with age-related cognitive impairment.Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology.Characterization of age-related changes in synaptic transmission onto F344 rat basal forebrain cholinergic neurons using a reduced synaptic preparationThe dysregulation of intracellular calcium in Alzheimer disease.Neuronal calcium signaling, mitochondrial dysfunction, and Alzheimer's disease.Presenilins function in ER calcium leak and Alzheimer's disease pathogenesis.Calcium signaling in cognition and aging-dependent cognitive decline.Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.Calcium channel blockers and dementia.Biological function of Presenilin and its role in AD pathogenesisNeuroglia in ageing and disease.Gene expression profiling predicts pathways and genes associated with Parkinson's disease.Vitamin D, reactive oxygen species and calcium signalling in ageing and disease.Calcium's role as nuanced modulator of cellular physiology in the brain.
P2860
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P2860
The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The importance of being subtle ...... itive decline in normal aging.
@en
type
label
The importance of being subtle ...... itive decline in normal aging.
@en
prefLabel
The importance of being subtle ...... itive decline in normal aging.
@en
P2860
P1433
P1476
The importance of being subtle ...... itive decline in normal aging.
@en
P2093
Emil C Toescu
P2860
P304
P356
10.1111/J.1474-9726.2007.00296.X
P577
2007-06-01T00:00:00Z