Are MAP kinases drug targets? Yes, but difficult ones.

Are MAP kinases drug targets? Yes, but difficult ones.

Item
http://www.wikidata.org/entity/Q36836817
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanismRoles of prohibitin in growth control and tumor suppression in human cancersIn vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening.A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.A computational workflow for the design of irreversible inhibitors of protein kinases.Activity prediction and structural insights of extracellular signal-regulated kinase 2 inhibitors with molecular dynamics simulations.A Comprehensive Structural Overview of p38α Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders.Frontiers in Medicinal Chemistry 2009--a summary of the meeting at Heidelberg University.Role of Molecular Interactions and Protein Rearrangement in the Dissociation Kinetics of p38α MAP Kinase Type-I/II/III Inhibitors.Assessing protein kinase selectivity with molecular dynamics and mm-pbsa binding free energy calculations.
P2860

Are MAP kinases drug targets? Yes, but difficult ones.

Item
http://www.wikidata.org/entity/Q36836817
description
2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年论文
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2007年论文
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2007年论文
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name
Are MAP kinases drug targets? Yes, but difficult ones.
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type
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Are MAP kinases drug targets? Yes, but difficult ones.
@en
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Are MAP kinases drug targets? Yes, but difficult ones.
@en
P1433
P1476
P2093
P2860
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P356
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Are MAP kinases drug targets? Yes, but difficult ones.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698