Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins.
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The Role of Bone Marrow Microenvironment in Governing the Balance between Osteoblastogenesis and AdipogenesisTumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitisRole of TNF alpha and PLF in bone remodeling in a rat model of repetitive reaching and graspingProlonged performance of a high repetition low force task induces bone adaptation in young adult rats, but loss in mature rats.Elevated Lifetime Lead Exposure Impedes Osteoclast Activity and Produces an Increase in Bone Mass in Adolescent MiceDose effect of tumor necrosis factor-alpha on in vitro osteogenic differentiation of mesenchymal stem cells on biodegradable polymeric microfiber scaffolds.NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.The effects of proteasome inhibitors on bone remodeling in multiple myeloma.Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity.Msx2 mediates the inhibitory action of TNF-alpha on osteoblast differentiation.Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB.Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.Smurf1 inhibits mesenchymal stem cell proliferation and differentiation into osteoblasts through JunB degradation.High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment.Harnessing and modulating inflammation in strategies for bone regeneration.Glucocorticoids and tumor necrosis factor α increase oxidative stress and suppress Wnt protein signaling in osteoblastsStudent Award for Outstanding Research Winner in the Ph.D. Category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: The interplay of bone-like extracellular matrix and TNF-α signaling on in vitro osteogenic differentiation oCyclic AMP Response Element-binding Protein H (CREBH) Mediates the Inhibitory Actions of Tumor Necrosis Factor α in Osteoblast Differentiation by Stimulating Smad1 Degradation.Diabetes aggravates periodontitis by limiting repair through enhanced inflammation.Identification of C-terminal Hsp70-interacting protein as a mediator of tumour necrosis factor action in osteoblast differentiation by targeting osterix for degradationThe ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis.Trauma-induced heterotopic bone formation and the role of the immune system: A reviewHeavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signalingInflammation, fracture and bone repair.Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk.Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migrationUbiquitin e3 ligase itch negatively regulates osteoblast differentiation from mesenchymal progenitor cellsThe Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis.Ubiquitin E3 ligase Itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.Post-translational Regulation of Runx2 in Bone and Cartilage.Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging.Deregulation of bone forming cells in bone diseases and anabolic effects of strontium-containing agents and biomaterials.Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteinsSmurf control in bone cells.Rodent models of aging bone: an update.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis.Initiation and early control of tissue regeneration - bone healing as a model system for tissue regeneration.EGF Inhibits Wnt/β-Catenin-Induced Osteoblast Differentiation by Promoting β-Catenin Degradation.Suppression of NF-κB activation by gentian violet promotes osteoblastogenesis and suppresses osteoclastogenesis.
P2860
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P2860
Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ubiquitin ligase Smurf1 mediat ...... phogenetic signaling proteins.
@en
type
label
Ubiquitin ligase Smurf1 mediat ...... phogenetic signaling proteins.
@en
prefLabel
Ubiquitin ligase Smurf1 mediat ...... phogenetic signaling proteins.
@en
P2093
P2860
P356
P1476
Ubiquitin ligase Smurf1 mediat ...... phogenetic signaling proteins.
@en
P2093
Brendan F Boyce
David G Reynolds
Edward M Schwarz
Hani A Awad
Laura Yanoso
Lianping Xing
Motozo Yamashita
Qian Zhang
P2860
P304
23084-23092
P356
10.1074/JBC.M709848200
P407
P577
2008-06-19T00:00:00Z