Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling. - Wikidata - awgldk - TriplyDB

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.

http://www.wikidata.org/entity/Q36838890

about

pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC)Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate Molecular details of cAMP generation in mammalian cells: a tale of two systems AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells Nitric oxide and pH modulation in gynaecological cancer Molecular mechanisms and regulation of urinary acidification Role of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulation Investigation of cAMP microdomains as a path to novel cancer diagnostics Regulation of nephron water and electrolyte transport by adenylyl cyclases The role of soluble adenylyl cyclase in neurite outgrowth Loss of the V-ATPase B1 subunit isoform expressed in non-neuronal cells of the mouse olfactory epithelium impairs olfactory function Structure and proposed mechanism for the pH-sensing Helicobacter pylori chemoreceptor TlpB Intracellular cAMP signaling by soluble adenylyl cyclase.Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites Regulation of epithelial function, differentiation, and remodeling in the epididymis Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ Aromatase is increased in astrocytes in the presence of elevated pressure Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1 Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cells Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice Transepithelial projections from basal cells are luminal sensors in pseudostratified epithelia Cyclic 3',5'-AMP causes ADAM1/ADAM2 to rapidly diffuse within the plasma membrane of guinea pig sperm cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells.Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.Structure-based development of novel adenylyl cyclase inhibitors Segmental expression of the bradykinin type 2 receptor in rat efferent ducts and epididymis and its role in the regulation of aquaporin 9.Role of purinergic signaling pathways in V-ATPase recruitment to apical membrane of acidifying epididymal clear cells.Regulation of proximal tubule vacuolar H(+)-ATPase by PKA and AMP-activated protein kinase.Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.Absence of estrogen receptor alpha leads to physiological alterations in the mouse epididymis and consequent defects in sperm function Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR.Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors.Sensing, signaling and sorting events in kidney epithelial cell physiology.

P2860

Q21129238-56D1F7BE-DBFD-42A1-8EBC-3579BB42B0EE Q21144234-EF640C01-9C47-4240-9F9B-4B9C200DEBD1 Q24338288-37CA6615-807C-4D6E-A94E-75B6D1C8A232 Q24622606-A67B3F7F-C644-46B8-A043-49BC7D5526EE Q24657352-47C41803-7F55-4E3D-9D52-C77D671E4CA8 Q26741063-62F4DC12-86E3-4441-B134-4997562408EC Q26823086-0997F939-6109-4E0C-B641-40E9D415D99C Q26828035-A8A1E5B4-97C8-49B1-853E-A08FB98DE1FA Q27023080-8AB19C61-2966-4FD8-89F8-120A73145327 Q27023655-6E4A46D3-2903-4502-A690-2C4732877B33 Q27028148-62A9103B-4A32-45E0-83C1-EFEF441FBFFC Q27318215-90346F27-9E4E-4EF2-B36F-D509C1682C47 Q27681189-BFE22709-90DD-44F3-AFFF-5762D4D1FAA6 Q27691286-3D641564-0D06-4658-8959-D35C5A00D143 Q27974564-677EBD0C-2A52-4EA0-A940-B753C808728F Q28081095-3654A310-435C-4A47-8D7A-2AF51BE8B401 Q28512781-65027884-7833-4A15-A243-C2979BB459FC Q28566043-CE4E1E35-8E5D-4D34-8B4D-605C33ACAE42 Q28569209-76E85AF9-2DCA-44E1-AD3E-0BEC9762B111 Q28577068-BABEBC06-A2CA-41F4-90E8-DC1F29331EB7 Q28577214-57205604-E5C4-49AC-9477-917207876C79 Q28583173-B08993B3-0F3B-4156-9479-F94797017E2D Q28583885-17070379-F5CD-4E22-ADB1-BE29176E9EBC Q28588238-911836F8-6594-4746-9E73-9FF2959E6279 Q30486105-76F06FA6-3ACA-4B3D-865D-FE6DADDD2ED5 Q30489017-31A0E745-7823-4F35-8254-5367F5535F22 Q30493671-A5190FD1-D8F0-4D28-B889-29DC39F24C97 Q30539548-A26C11DB-6EEF-4220-85AA-89A79A6B507C Q30539902-7E4EFA24-0BDF-4F4D-B47B-2A992860F62A Q33352228-B68B7A06-06A4-4DEE-8838-0604FDE7417B Q33373249-C8F8BDA8-2E16-4CDB-9F60-335D461148D4 Q33523672-88A7AF04-8C8D-4950-8758-3141E8C0F786 Q33568911-2CF1484E-B708-4884-8A28-740118A1F6E3 Q33591748-A7225DD5-13DA-4184-964D-315C23D5C3D1 Q33694769-B41A77C6-BFBC-43FD-8A75-C2244183D91E Q33802303-3639EF68-5CBF-490D-A1C0-A3DED3B869F7 Q33840526-C45CE18F-4767-4571-B666-D156369E9F40 Q33944537-53AB69F9-19F2-4126-97E1-DAD6E033E68D Q33959083-F155F765-7314-4013-9FF2-B6EE70052511 Q33961141-CF43C40B-A6A1-41AB-A85C-8374906E0F58

P2860

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.

http://www.wikidata.org/entity/Q36838890

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Bicarbonate-regulated adenylyl ...... -dependent V-ATPase recycling.

@en

type

label

Bicarbonate-regulated adenylyl ...... -dependent V-ATPase recycling.

@en

prefLabel

Bicarbonate-regulated adenylyl ...... -dependent V-ATPase recycling.

@en

P1433

Q36838890-BD0A89A2-2E78-4977-9033-C6A4FA655D2A

P1476

Q36838890-D7B8A40A-C5F8-4826-B99B-05B609F09B83

P2093

Q36838890-1803A8FD-F28B-4FBB-A0B7-8BFBCD242FBE

Q36838890-18C5BD8D-5A71-48C1-A17E-3BD16BF52D2A

Q36838890-35483CC7-E897-42E7-A8CE-FF5D09759E76

Q36838890-B43BD299-6A8C-461A-A9E0-E318897C3CC9

Q36838890-C7692F7C-5204-425B-AD73-D461EEBFE168

Q36838890-C9DC3576-DF30-4DA7-8E58-92E12A459BB9

Q36838890-DFEF467C-1758-49D0-80CD-8823BB08F243

Q36838890-EB2333A6-C7F7-431A-B229-3FE9A5BCA1E8

P2860

Q36838890-0A0148A1-98E2-4BDB-B428-16244B721F5B

Q36838890-221D10C1-14D7-434B-89CB-EE2624649023

Q36838890-3251CF2A-F023-4B02-AE38-18F6E05483AE

Q36838890-3D029DCA-4059-462C-BAF5-8C61B2A64BC2

Q36838890-5406D6D7-433C-4CC1-AE1D-E7794D1DD65E

Q36838890-5AEE7717-2552-4508-A806-8BB810AAFD1D

Q36838890-5DD90040-18FD-4828-890E-CDEC574750B1

Q36838890-607F48E4-BF74-4852-BD13-E7CB70941DDF

Q36838890-7208887F-7C0A-4336-8EE3-E9F342C8A36E

Q36838890-81F64569-9651-48F1-A8EB-D1CEE839F337

P304

Q36838890-F20D66AA-683A-4FA0-8772-831B4CEEFA92

P31

Q36838890-935A0587-78FF-4C10-B606-47652C260899

P356

Q36838890-F057AD04-BDC8-44E9-BFFC-CFB67DDC77B9

P407

Q36838890-D20109BB-A29C-47CC-8A3F-A0590E0DED3A

P433

Q36838890-CE30F8FD-2CCB-43D0-AB38-8FE8FA4693A8

P478

Q36838890-472D8964-6112-4750-86D2-19FAB61D0C38

P50

Q36838890-9483242C-AE3C-42BE-9D65-6788D6C8DF9D

P577

Q36838890-5A624826-A799-4E34-8F16-CC2D9FF41CCE

P698

Q36838890-75B5FB35-3D6E-4894-A57D-5B590A7E9395

P932

Q36838890-3C189A22-ACF1-4ECB-9C1B-E8B1078015F0

P356

P1433

Journal of Biological Chemistry

P1476

Bicarbonate-regulated adenylyl ...... -dependent V-ATPase recycling.

@en

P2093

Dennis Brown

http://www.w3.org/2001/XMLSchema#string

Lonny R Levin

http://www.w3.org/2001/XMLSchema#string

Nicolas Da Silva

http://www.w3.org/2001/XMLSchema#string

Nuria Pastor-Soler

http://www.w3.org/2001/XMLSchema#string

Sylvie Breton

http://www.w3.org/2001/XMLSchema#string

Tatiana N Litvin

http://www.w3.org/2001/XMLSchema#string

Valerie Beaulieu

http://www.w3.org/2001/XMLSchema#string

Yanqiu Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells

The ins and outs of aquaporin-2 trafficking

Acidification of the male reproductive tract by a proton pumping (H+)-ATPase

Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM

Specific expression of soluble adenylyl cyclase in male germ cells

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase.

Regulated trafficking of the CFTR chloride channel.

Bicarbonate-regulated soluble adenylyl cyclase.

P304

49523-49529

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M309543200

http://www.w3.org/2001/XMLSchema#string

P407

P433

49

http://www.w3.org/2001/XMLSchema#string

P478

278

http://www.w3.org/2001/XMLSchema#string

P50

P577

2003-09-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

14512417

http://www.w3.org/2001/XMLSchema#string

P932

3652382

http://www.w3.org/2001/XMLSchema#string