Mutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.
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Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insightsStructure-activity relationship studies of the two-component lantibiotic haloduracinCyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptidesStructural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteriaHigh divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis.A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.Photochemical cleavage of leader peptides.Nine post-translational modifications during the biosynthesis of cinnamycin.Pseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides.Michael-type cyclizations in lantibiotic biosynthesis are reversible.Product Formation by the Promiscuous Lanthipeptide Synthetase ProcM is under Kinetic Control.Biosynthesis of the class III lantipeptide catenulipeptinDiscovery and Characterization of Bicereucin, an Unusual d-Amino Acid-Containing Mixed Two-Component Lantibiotic.Leader Peptide Establishes Dehydration Order, Promotes Efficiency, and Ensures Fidelity During Lacticin 481 Biosynthesis.In vitro reconstitution and substrate specificity of a lantibiotic protease.The importance of the leader sequence for directing lanthionine formation in lacticin 481.Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry.Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.Mathermycin, a Lantibiotic from the Marine Actinomycete Marinactinospora thermotolerans SCSIO 00652.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Gene cluster for biosynthesis of thermophilin 1277--a lantibiotic produced by Streptococcus thermophilus SBT1277, and heterologous expression of TepI, a novel immunity peptide.Identification of the Biosynthesis Gene Cluster for the Novel Lantibiotic Paenilan from Paenibacillus polymyxa E681 and Characterization of its Product.Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase familyCharacterization of the stereochemical configuration of lanthionines formed by the lanthipeptide synthetase GeoM.Incorporation of Nonproteinogenic Amino Acids in Class I and II Lantibiotics.
P2860
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P2860
Mutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
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2007年论文
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2007年论文
@zh-cn
name
Mutants of the zinc ligands of ...... impaired cyclization activity.
@en
type
label
Mutants of the zinc ligands of ...... impaired cyclization activity.
@en
prefLabel
Mutants of the zinc ligands of ...... impaired cyclization activity.
@en
P2860
P356
P1433
P1476
Mutants of the zinc ligands of ...... impaired cyclization activity
@en
P2093
Gregory C Patton
Moushumi Paul
P2860
P304
P356
10.1021/BI7000104
P407
P577
2007-05-05T00:00:00Z