Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
about
Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population.The chemical disruption of human metabolism.Folding correction of ABC-transporter ABCB1 by pharmacological chaperones: a mechanistic concept.Human Excretion of Polybrominated Diphenyl Ether Flame Retardants: Blood, Urine, and Sweat Study.When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus) populations.Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency.Geographic Differences in Persistent Organic Pollutant Levels of Yellowfin Tuna.Location Is Everything: The Pollutants in Yellowfin Tuna Depend on Where It's Caught.Assaying uptake of endocrine disruptor compounds in zebrafish embryos and larvae.Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.Coarse-grained molecular dynamics simulations reveal lipid access pathways in P-glycoprotein.
P2860
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P2860
Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Global marine pollutants inhib ...... fects, and cocrystal structure
@en
type
label
Global marine pollutants inhib ...... fects, and cocrystal structure
@en
prefLabel
Global marine pollutants inhib ...... fects, and cocrystal structure
@en
P2093
P2860
P356
P1433
P1476
Global marine pollutants inhib ...... fects, and cocrystal structure
@en
P2093
Aaron P McGrath
Amro Hamdoun
Geoffrey Chang
Greg Loewen
Lindsay T Bonito
Lydia M Vermeer
Steven D Rees
Stuart Sandin
Tufan Gökirmak
P2860
P304
P356
10.1126/SCIADV.1600001
P577
2016-04-15T00:00:00Z