Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10. - Wikidata - awgldk - TriplyDB

Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10.

Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10.

http://www.wikidata.org/entity/Q36845225

about

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity Atg5-independent sequestration of ubiquitinated mycobacteria.Bacteria modulate the CD8+ T cell epitope repertoire of host cytosol-exposed proteins to manipulate the host immune response.Secreted immunodominant Mycobacterium tuberculosis antigens are processed by the cytosolic pathway.Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.Lipids, apoptosis, and cross-presentation: links in the chain of host defense against Mycobacterium tuberculosis.Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination T cell monitoring of chemotherapy in experimental rat tuberculosis.Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection.Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection MHC molecules and microbial antigen processing in phagosomes.Evasion and subversion of antigen presentation by Mycobacterium tuberculosis.T cells in mycobacterial infection and disease.Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?Antigen-specific CD8(+) T cells and protective immunity to tuberculosis.Release of mycobacterial antigens.Type I, II, and III Interferons: Regulating Immunity to Mycobacterium tuberculosis Infection.The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses.Identification of Mycobacterial RplJ/L10 and RpsA/S1 Proteins as Novel Targets for CD4+ T Cells.Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients.Cross-priming induces immunodomination in the presence of viral MHC class I inhibition.Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages.Prime-boost BCG vaccination with DNA vaccines based in β-defensin-2 and mycobacterial antigens ESAT6 or Ag85B improve protection in a tuberculosis experimental model.

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P2860

Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10.

http://www.wikidata.org/entity/Q36845225

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Bacterial protein secretion is ...... um tuberculosis antigen CFP10.

@en

type

label

Bacterial protein secretion is ...... um tuberculosis antigen CFP10.

@en

prefLabel

Bacterial protein secretion is ...... um tuberculosis antigen CFP10.

@en

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Infection and Immunity

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Bacterial protein secretion is ...... um tuberculosis antigen CFP10.

@en

P2093

Joshua S Woodworth

http://www.w3.org/2001/XMLSchema#string

Sarah M Fortune

http://www.w3.org/2001/XMLSchema#string

P2860

Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells

A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family

Mutually dependent secretion of proteins required for mycobacterial virulence.

Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

Genetic requirements for mycobacterial survival during infection

Comparative genomics of BCG vaccines by whole-genome DNA microarray

P304

4199-4205

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scholarly article

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10.1128/IAI.00307-08

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9

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76

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Samuel M. Behar

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2008-06-30T00:00:00Z

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5260733

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18591224

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Mycobacterium tuberculosis

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2519428

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