Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle
about
Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation.Abundance of prereplicative complexes (Pre-RCs) facilitates recombinational repair under replication stress in fission yeastProteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entryPost-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer.MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma.How dormant origins promote complete genome replication.MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.Effect of minichromosome maintenance protein 2 deficiency on the locations of DNA replication origins.Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development.Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatmentOverexpression of CDT1 Is a Predictor of Poor Survival in Patients with Hepatocellular Carcinoma.Ets transcription factor GABP controls T cell homeostasis and immunity.Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression.Investigating the role of Rts1 in DNA replication initiation.
P2860
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P2860
Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reducing MCM levels in human p ...... ty during the first cell cycle
@en
type
label
Reducing MCM levels in human p ...... ty during the first cell cycle
@en
prefLabel
Reducing MCM levels in human p ...... ty during the first cell cycle
@en
P2093
P2860
P356
P1433
P1476
Reducing MCM levels in human p ...... ty during the first cell cycle
@en
P2093
B Czepulkowski
N S B Thomas
P2860
P2888
P304
P356
10.1038/ONC.2010.138
P407
P577
2010-05-03T00:00:00Z