Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases - Wikidata - awgldk - TriplyDB

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

http://www.wikidata.org/entity/Q24564474

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Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint Interactions of the human MCM-BP protein with MCM complex components and Dbf4 Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation Replication licensing and cancer--a fatal entanglement?Preventing re-replication of chromosomal DNA.Mechanisms to control rereplication and implications for cancer.Cdc7-Dbf4 and the human S checkpoint response to UVC The Mcm2-7 replicative helicase: a promising chemotherapeutic target ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma A structure-specific nucleic acid-binding domain conserved among DNA repair proteins Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns Mcm2 phosphorylation and the response to replicative stress The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.Preventing replication fork collapse to maintain genome integrity CDC6: from DNA replication to cell cycle checkpoints and oncogenesis Regulation of replication fork progression through histone supply and demand Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases Hpz1 modulates the G1-S transition in fission yeast The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase ATR: an essential regulator of genome integrity Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor Udu deficiency activates DNA damage checkpoint.Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage.Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations.RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.Function of the ATR N-terminal domain revealed by an ATM/ATR chimera.ATM-mediated transcriptional and developmental responses to gamma-rays in Arabidopsis Differential requirements for MCM proteins in DNA replication in Drosophila S2 cells Mcm4 C-terminal domain of MCM helicase prevents excessive formation of single-stranded DNA at stalled replication forks Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.HARPing on about the DNA damage response during replication.Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells.

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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

http://www.wikidata.org/entity/Q24564474

description

2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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name

Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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type

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Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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prefLabel

Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

@ast

Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

@en

Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

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PNAS.0403410101

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Minichromosome maintenance pro ...... ATM and ATR checkpoint kinases

@en

P2093

David Cortez

http://www.w3.org/2001/XMLSchema#string

Gloria Glick

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P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase

Human papillomavirus oncoprotein E6 binds to the C-terminal region of human minichromosome maintenance 7 protein

MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3

Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

Uninterrupted MCM2-7 function required for DNA replication fork progression.

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10078-83

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scholarly article

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4027721

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10.1073/PNAS.0403410101

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P407

P433

27

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101

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Stephen Elledge

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2004-07-06T00:00:00Z

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8497164

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15210935

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454167

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