A peptide antagonist of CD28 signaling attenuates toxic shock and necrotizing soft-tissue infection induced by Streptococcus pyogenes.
about
Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila.Single administration of p2TA (AB103), a CD28 antagonist peptide, prevents inflammatory and thrombotic reactions and protects against gastrointestinal injury in total-body irradiated miceCD4+ T cells promote the pathogenesis of Staphylococcus aureus pneumonia.CD28 homodimer interface mimetic peptide acts as a preventive and therapeutic agent in models of severe bacterial sepsis and gram-negative bacterial peritonitis.Innate Immune Signaling Activated by MDR Bacteria in the AirwayCD28: direct and critical receptor for superantigen toxinsUpdate on staphylococcal superantigen-induced signaling pathways and therapeutic interventions.Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction.Bacterial superantigen toxins induce a lethal cytokine storm by enhancing B7-2/CD28 costimulatory receptor engagement, a critical immune checkpoint.CD28 Costimulation: From Mechanism to Therapy.
P2860
Q33798775-6066C37B-B090-43F1-B394-77C8289A9938Q35211498-6351C1E3-A4E9-4EE0-9A53-20C11BD6054BQ35474220-E32B4467-574B-4940-BD63-E789303CB399Q35558842-5219042C-331F-4AF6-9C7A-6F6E5A6BE630Q36422470-6F57F133-9FA9-4C1F-B408-8EBA835B6FACQ37235239-AC45B443-9774-4F4A-93A3-9001682AD93BQ37235247-54C90513-BAD9-4883-B4DF-0C064A68FA53Q37369456-0EBEA8ED-43B2-4421-9A79-5002690A7E51Q37686685-A6283682-5460-4E68-A987-03872694ABBEQ38837466-FC2F4A22-138C-41ED-8791-04B674D5B535
P2860
A peptide antagonist of CD28 signaling attenuates toxic shock and necrotizing soft-tissue infection induced by Streptococcus pyogenes.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A peptide antagonist of CD28 s ...... ced by Streptococcus pyogenes.
@en
type
label
A peptide antagonist of CD28 s ...... ced by Streptococcus pyogenes.
@en
prefLabel
A peptide antagonist of CD28 s ...... ced by Streptococcus pyogenes.
@en
P2093
P2860
P356
P1476
A peptide antagonist of CD28 s ...... ced by Streptococcus pyogenes.
@en
P2093
Alan S Cross
Anat Shirvan
Cinzia Benazzi
Girish Ramachandran
Kristina M Harris
Louis J Detolla
Mohan E Tulapurkar
Raymond Kaempfer
Ronen Shemesh
P2860
P304
P356
10.1093/INFDIS/JIT104
P407
P577
2013-03-14T00:00:00Z