Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation.
about
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complexPhosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lckThe human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activityInterleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell lineThe protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagementReconstitution of the B cell antigen receptor signaling components in COS cellsExpression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell linesHerpes simplex virus requires VP11/12 to induce phosphorylation of the activation loop tyrosine (Y394) of the Src family kinase Lck in T lymphocytes.Characterization of the in vivo sites of serine phosphorylation on Lck identifying serine 59 as a site of mitotic phosphorylation.Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acidsInteraction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase.Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of LckFibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus SaimiriCorrelation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor.Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains.Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transductionPolyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domainsKinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance.The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell linesInduction of a cytoplasmic activator of DNA synthesis in lymphocytes is mediated through a membrane-associated protein kinase.Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes.Selective expression of alternative lck mRNAs in human malignant cell lines.Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization.Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation.Signaling defects in anti-tumor T cellsThe lymphocyte-specific tyrosine protein kinase p56lck.Defective expression of p56lck in an infant with severe combined immunodeficiency.T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck.Purification and initial characterization of the lymphoid-cell protein-tyrosine kinase p56lck from a baculovirus expression system.Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation.Autonomous roles for the cytoplasmic domains of the CD2 and CD4 T cell surface antigens.Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri.HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.Down-regulation of lck mRNA by T cell activation involves transcriptional and post-transcriptional mechanisms.
P2860
Q24293680-A731E8A4-C574-4962-A3C1-11C4DECA475AQ24309126-48B7CF72-56D9-41FC-9457-4B9168789447Q24555677-4455FC8B-6875-40B6-AD03-14664733BDDBQ24562381-DF6086A0-9CFE-4705-BEF7-D3AD89DE83E6Q28296153-7A303D8A-78AB-40BB-BF22-933FF9679FFFQ28615625-35F9BF0B-7762-4D56-BAFC-720C2C029DEDQ28615680-3CB01ED4-2461-487E-A2C6-8DC21CA54BA8Q28647261-F3AA0D68-C086-464E-BBF7-EBA8E29DEC4DQ30157107-D7D0B416-71C4-447F-B407-9823DFE2DE65Q30167598-E24D0D26-C56C-427D-B861-626A16619457Q33781622-2BC1AD84-4294-4693-9042-4B6EA7E119CFQ34115915-1AF4FB82-F09E-47EC-928A-1F986B37649EQ34297751-42978252-3A9F-4687-B42C-8E379537DF62Q34763949-99745C61-A9C4-4C39-A948-470CCE7A9BC6Q35592444-29842F58-A3DB-4262-A531-D285A5CB4E1FQ35879209-03399B48-A5B2-49D6-AB4D-32426093E168Q36105675-0B84CB0C-F3DB-4FF5-BAE7-D1ED17A83B6CQ36257685-33D2EF8C-73D6-40A8-B719-245921AD8E54Q36286325-DBAD475B-A6DB-45EB-B9A4-9E34B0412335Q36288228-4F14706B-B62E-4BBA-906F-47AB6A33F27DQ36325295-4D9BCE46-0754-4F10-A429-8B5AE0475405Q36669879-1A28619F-B6B5-4F7A-8AAB-751D4C90DBB9Q36693815-4440D3FD-F5E8-4FD9-BE30-2437D40E8F1EQ36741485-49A70E96-DF4E-4AD2-B815-A9BC2A8822E2Q36762437-04F46A9A-619D-499D-BC3A-41DC35A72D03Q36769667-4CD5DDC1-8290-41BE-931F-14E73B85BB85Q36777775-B78578F6-0028-437B-8FBE-8A62D7E9009EQ36806641-22988EE6-D5B7-4EAD-B8D4-7F87A4350C2AQ36817419-25DA4758-2105-4284-A154-A6178A9109BBQ36963443-9DADC529-4C87-4B1F-B3FC-79684BC538D1Q37063739-584BF71F-8B15-4C71-8348-4AB7BF99DF1BQ37102372-CBBB3450-18FD-4774-83F0-A0639846F5FEQ37383981-47A36E38-F10C-4BE3-AC20-3B6A016D9DF4Q37422934-5AEF133D-1649-43FF-9158-494088284403Q37548959-B5D17DF7-984E-43C6-AB34-2C4938A1D3C1Q38262262-A4AC38EB-426D-4EBA-B7C6-73F154D2E680Q38336914-EFE67623-EF65-42C6-931D-B0D4437087D4Q38821895-3C7C1A84-1E8E-41BD-A308-32889C9D8477Q40283606-2E0ABEE8-A943-40C0-BE63-9A7358B391A8Q40506537-B5A4D2E2-F242-4A97-BAD0-DA6FC8AE4BC1
P2860
Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Alterations of the lymphocyte- ...... lck) during T-cell activation.
@en
type
label
Alterations of the lymphocyte- ...... lck) during T-cell activation.
@en
prefLabel
Alterations of the lymphocyte- ...... lck) during T-cell activation.
@en
P2093
P2860
P356
P1476
Alterations of the lymphocyte- ...... lck) during T-cell activation.
@en
P2093
P2860
P304
P356
10.1128/MCB.8.10.4353
P407
P577
1988-10-01T00:00:00Z