Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.
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Building a ninefold symmetrical barrel: structural dissections of centriole assemblyStructure of the SAS-6 cartwheel hub from Leishmania majorThe Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication FactorStructure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 KinasesThe PLK4-STIL-SAS-6 module at the core of centriole duplicationMutation in PLK4, encoding a master regulator of centriole formation, defines a novel locus for primordial dwarfism.The centriole duplication cycle.SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplicationDirect interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix.The centrosome and its duplication cycleProtein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication.The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.Drosophila Ana1 is required for centrosome assembly and centriole elongation.Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint.Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation.Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance.Polo-like kinases: structural variations lead to multiple functions.Cartwheel assembly.Molecular and cellular basis of autosomal recessive primary microcephaly.Binding of STIL to Plk4 activates kinase activity to promote centriole assemblyThe Centriole Cartwheel Protein SAS-6 in Trypanosoma brucei Is Required for Probasal Body Biogenesis and Flagellum Assembly.Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro.Plk4-dependent phosphorylation of STIL is required for centriole duplication.The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.Interaction between the C. elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly.Once and only once: mechanisms of centriole duplication and their deregulation in disease.Revisiting Centrioles in Nematodes-Historic Findings and Current Topics
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P2860
Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Direct binding of SAS-6 to ZYG ...... triole for cartwheel assembly.
@en
type
label
Direct binding of SAS-6 to ZYG ...... triole for cartwheel assembly.
@en
prefLabel
Direct binding of SAS-6 to ZYG ...... triole for cartwheel assembly.
@en
P2093
P2860
P50
P1433
P1476
Direct binding of SAS-6 to ZYG ...... triole for cartwheel assembly.
@en
P2093
Andrew K Shiau
Arshad Desai
Molly M Lettman
Sheng-Hong Chen
Sherry Niessen
Valeria Viscardi
P2860
P304
P356
10.1016/J.DEVCEL.2013.03.011
P407
P577
2013-05-01T00:00:00Z