Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes.
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The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen speciesDown-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibitionNef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathwaysHIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesisHIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell-cycle mechanisms contributing to the proliferative phenotype in HIV-associated nephropathy.HIV-associated neurocognitive disorder--pathogenesis and prospects for treatmentPodocyte pathology and nephropathy - sphingolipids in glomerular diseasesRole of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferationCardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudineTemporal profile of the renal transcriptome of HIV-1 transgenic mice during disease progressionBeta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation.Nuclear targeting of macromolecular polyanions by an HIV-Tat derived peptide. Role for cell-surface proteoglycans.Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome.Rhabdomyolysis as the first manifestation of human immunodeficiency virus infectionHIV-1 Vpr inhibits cytokinesis in human proximal tubule cellsHIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation.Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like diseaseRhesus macaques infected with macrophage-tropic simian immunodeficiency virus (SIVmacR71/17E) exhibit extensive focal segmental and global glomerulosclerosis.Pro-atherogenic shear stress and HIV proteins synergistically upregulate cathepsin K in endothelial cells.Renal HIV expression is unaffected by serum LPS levels in an HIV transgenic mouse model of LPS induced kidney injury.The basic domain of HIV-tat transactivating protein is essential for its targeting to lipid rafts and regulating fibroblast growth factor-2 signaling in podocytes isolated from children with HIV-1-associated nephropathy.HIV-associated nephropathy: role of mammalian target of rapamycin pathway.Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosisTat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders.DC-specific ICAM-3-grabbing nonintegrin mediates internalization of HIV-1 into human podocytes.Elevated levels of tumor necrosis factor alpha (TNF-alpha) in human immunodeficiency virus type 1-transgenic mice: prevention of death by antibody to TNF-alpha.Modulation of renin angiotensin system predominantly alters sclerotic phenotype of glomeruli in HIVAN.Biophysical properties of normal and diseased renal glomeruli.Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphologyIdentification of the nephropathy-susceptibility locus HIVAN4APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathyTransforming growth factor-beta in disease: the dark side of tissue repair.HIV gene expression deactivates redox-sensitive stress response program in mouse tubular cells both in vitro and in vivo.HIV-associated nephropathy: role of AT2R.Stimulation of alpha 1 (I) procollagen gene expression in NIH-3T3 cells by the human T cell leukemia virus type 1 (HTLV-1) Tax gene.Human immunodeficiency virus-1 gp120 and gp160 envelope proteins modulate mesangial cell gelatinolytic activity.Endothelial dysfunction, arterial stiffening, and intima-media thickening in large arteries from HIV-1 transgenic miceRoflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure.Can we cure HIV-1-associated nephropathy in transgenic mice?Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition.
P2860
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P2860
Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Progressive glomerulosclerosis ...... deficiency virus type 1 genes.
@en
type
label
Progressive glomerulosclerosis ...... deficiency virus type 1 genes.
@en
prefLabel
Progressive glomerulosclerosis ...... deficiency virus type 1 genes.
@en
P2093
P2860
P356
P1476
Progressive glomerulosclerosis ...... deficiency virus type 1 genes.
@en
P2093
Bruggeman LA
Klotman ME
Klotman PE
Marinos NJ
Notkins AL
P2860
P304
P356
10.1073/PNAS.89.5.1577
P407
P577
1992-03-01T00:00:00Z