Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests. - Wikidata - awgldk - TriplyDB

Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests.

Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests.

http://www.wikidata.org/entity/Q36850061

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Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory Single dose of morphine produced a prolonged effect on dopamine neuron activities Dyadic social interaction inhibits cocaine-conditioned place preference and the associated activation of the accumbens corridor Excessive cocaine use results from decreased phasic dopamine signaling in the striatum The Two Faces of Social Interaction Reward in Animal Models of Drug Dependence Differential effects of accumbens core vs. shell lesions in a rat concurrent conditioned place preference paradigm for cocaine vs. social interaction The development of a preference for cocaine over food identifies individual rats with addiction-like behaviors Naloxone's pentapeptide binding site on filamin A blocks Mu opioid receptor-Gs coupling and CREB activation of acute morphine Rat ultrasonic vocalizations demonstrate that the motivation to contextually reinstate cocaine-seeking behavior does not necessarily involve a hedonic response.Effects of lidocaine-induced inactivation of the bed nucleus of the stria terminalis, the central or the basolateral nucleus of the amygdala on the opponent-process actions of self-administered cocaine in rats Intermittent access to preferred food reduces the reinforcing efficacy of chow in rats.Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats.Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats Transitioning from First Drug Use to Dependence Onset: Illustration of a Multiparametric Approach for Comparative Epidemiology Behavioral, thermal and neurochemical effects of acute and chronic 3,4-methylenedioxymethamphetamine ("Ecstasy") self-administration.Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors A stimulus-control account of dysregulated drug intake.Reacquisition of cocaine conditioned place preference and its inhibition by previous social interaction preferentially affect D1-medium spiny neurons in the accumbens corridor Differences in social interaction- vs. cocaine reward in mouse vs. rat.Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology New vistas on cannabis use disorder.Regulation of operant oral ethanol self-administration: a dose-response curve study in rats.Intermittent (every-other-day) drinking induces rapid escalation of ethanol intake and preference in adolescent and adult C57BL/6J mice Increased conditioned place preference for cocaine in high anxiety related behavior (HAB) mice is associated with an increased activation in the accumbens corridor Shift from goal-directed to habitual cocaine seeking after prolonged experience in rats Brain-cocaine concentrations determine the dose self-administered by rats on a novel behaviorally dependent dosing schedule.Compulsive-like responding for opioid analgesics in rats with extended access.Cholinergic modulation of mesolimbic dopamine function and reward The motivation to self-administer is increased after a history of spiking brain levels of cocaine.Age-dependent morphine intake and cue-induced reinstatement, but not escalation in intake, by adolescent and adult male rats Escalation of food-maintained responding and sensitivity to the locomotor stimulant effects of cocaine in mice Examination of behavioral strategies regulating cocaine intake in rats.Dopamine Prediction Errors in Reward Learning and Addiction: From Theory to Neural Circuitry.A Single Amphetamine Infusion Reverses Deficits in Dopamine Nerve-Terminal Function Caused by a History of Cocaine Self-Administration.Escalation of cocaine intake with extended access in rats: dysregulated addiction or regulated acquisition?Sensitization to the motor stimulant effects of 3,4-methylenedioxypyrovalerone (MDPV) and cross-sensitization to methamphetamine in rats A review of preclinical research demonstrating that drug and non-drug reinforcers differentially affect behavior Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis Serotonergic mechanisms in addiction-related memories Augmentation of morphine-induced sensitization but reduction in morphine tolerance and reward in delta-opioid receptor knockout mice.

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Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests.

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Comparison of induced and independent major depressive disorders in 2,945 alcoholics

Emotion, decision making and the orbitofrontal cortex

Clinical features of cocaine-induced paranoia

Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers.

The neural basis of drug craving: an incentive-sensitization theory of addiction

Drug abuse: hedonic homeostatic dysregulation

Drug addiction, dysregulation of reward, and allostasis

Elimination of cocaine and metabolites in plasma, saliva, and urine following repeated oral administration to human volunteers.

Incentive-sensitization and addiction.

Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research.

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