Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
about
N-myc downstream-regulated gene 1 inhibits the proliferation and invasion of hepatocellular carcinoma cells via the regulation of integrin β3The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms.Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis.FAK-Src-paxillin system expression and disease outcome in human neuroblastoma.N4 -aryl substituted thiosemicarbazones derived from 1-indanones as potential anti-tumor agents for breast cancer treatment.The novel dithiocarbamate, DpdtC suppresses HER2-overexpressed cancer cells by up-regulating NDRG1 via inactivation of HER2-ERK 1/2 signaling.Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling.
P2860
Q33685302-25DF4375-23A9-4F2F-864C-8FA72EB2C2E1Q37291716-6E3338A3-361B-408A-9714-6D3BCB2D105BQ38873926-BD246655-8A30-4AEC-A297-2F9DB254F08EQ47299406-E15BC188-B6C7-48A9-BF5C-57F27EEC7E42Q47640263-C2FFAC07-A9F7-49F7-80C1-3DA30AB0338EQ48352498-358136D7-DB2B-43D2-AF41-47BB38CC75FEQ50314108-B8D4A67D-B81E-4C6C-91EA-46B169D7863DQ50944162-5E413E2A-4A06-44D0-9E88-3A56CF48EAEF
P2860
Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Targeting the Metastasis Suppr ...... ion Kinase/Paxillin Signaling.
@en
type
label
Targeting the Metastasis Suppr ...... ion Kinase/Paxillin Signaling.
@en
prefLabel
Targeting the Metastasis Suppr ...... ion Kinase/Paxillin Signaling.
@en
P2093
P2860
P50
P356
P1476
Targeting the Metastasis Suppr ...... sion Kinase/Paxillin Signaling
@en
P2093
Jiaoyang Lu
Kyung Chan Park
Minhua Zheng
Sharleen Menezes
Xiongzhi Wangpu
Zaklina Kovacevic
P2860
P304
P356
10.1124/MOL.115.103044
P577
2016-02-19T00:00:00Z