Appearances can be deceiving: phenotypes of knockout mice.
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The genetic signatures of noncoding RNAsEndogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissuesAltered immune response in mice deficient for the G protein-coupled receptor GPR34Function Over Form: Modeling Groups of Inherited Neurological Conditions in ZebrafishShadoo/PrP (Sprn(0/0) /Prnp(0/0) ) double knockout mice: more than zeroesDifferences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and miceGeneration and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular glandDisruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral PhenotypeMethylmercury Exposure Reduces the Auditory Brainstem Response of Zebra Finches (Taeniopygia guttata ).Improved knockdown from artificial microRNAs in an enhanced miR-155 backbone: a designer's guide to potent multi-target RNAiNew insights into behaviour using mouse ENU mutagenesisJuvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.Joint mouse-human phenome-wide association to test gene function and disease risk.The expanding role of mouse genetics for understanding human biology and diseaseENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2.Loss of hepatic DEPTOR alters the metabolic transition to fastingAllelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice.Distribution and Severity of Neuropathology in β-Mannosidase-Deficient Mice is Strain Dependent.Designing phenotyping studies for genetically engineered miceHsp70 regulates immune response in experimental autoimmune encephalomyelitisMIPHENO: data normalization for high throughput metabolite analysis.An RNAi-based approach to down-regulate a gene family in vivo.Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional thresholdBeyond faithful conduction: short-term dynamics, neuromodulation, and long-term regulation of spike propagation in the axon.Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to AnalysisNew approaches to the representation and analysis of phenotype knowledge in human diseases and their animal modelsProliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression.Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic diseaseHigh-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders.Fitness Assays Reveal Incomplete Functional Redundancy of the HoxA1 and HoxB1 Paralogs of MiceChronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and ageDifferential Sensitivity of Target Genes to Translational Repression by miR-17~92.A versatile transgenic allele for mouse overexpression studiesMouse fitness measures reveal incomplete functional redundancy of Hox paralogous group 1 proteinsComplex systems dynamics in aging: new evidence, continuing questions.The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models.Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.
P2860
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P2860
Appearances can be deceiving: phenotypes of knockout mice.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Appearances can be deceiving: phenotypes of knockout mice.
@en
type
label
Appearances can be deceiving: phenotypes of knockout mice.
@en
prefLabel
Appearances can be deceiving: phenotypes of knockout mice.
@en
P356
P1476
Appearances can be deceiving: phenotypes of knockout mice
@en
P2093
T Neil Dear
P304
P356
10.1093/BFGP/ELM008
P577
2007-06-20T00:00:00Z