The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae - Wikidata - awgldk - TriplyDB

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

http://www.wikidata.org/entity/Q36856671

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RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease The Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP Synthase Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Alterations in Mitochondrial Quality Control in Alzheimer's Disease The Role of Oxidative Stress-Induced Epigenetic Alterations in Amyloid-β Production in Alzheimer's Disease Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease Alzheimer's pathogenesis and its link to the mitochondrion Amyloid beta: multiple mechanisms of toxicity and only some protective effects?Mitochondrial dysfunction: different routes to Alzheimer's disease therapy Mitochondrial oxidative stress in aging and healthspan Maintenance of synaptic stability requires calcium-independent phospholipase A₂ activity Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway Real-time imaging and quantification of amyloid-beta peptide aggregates by novel quantum-dot nanoprobes Examining the interactome of huperzine A by magnetic biopanning Coenzyme Q10 protects human endothelial cells from β-amyloid uptake and oxidative stress-induced injury Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation Activation of PERK signaling attenuates Abeta-mediated ER stress.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation Unlocking the Door to Neuronal Woes in Alzheimer's Disease: Aβ and Mitochondrial Permeability Transition Pore Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus.TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β Sporadic inclusion body myositis: the genetic contributions to the pathogenesis.Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes.The Alzheimer's disease mitochondrial cascade hypothesis The novel amyloid-beta peptide aptamer inhibits intracellular amyloid-beta peptide toxicity Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.Potential therapeutic strategies for Alzheimer's disease targeting or beyond β-amyloid: insights from clinical trials Is Alzheimer's disease a systemic disease?A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.Potential therapeutic benefits of strategies directed to mitochondria.Alzheimer's proteins, oxidative stress, and mitochondrial dysfunction interplay in a neuronal model of Alzheimer's disease.

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P2860

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

http://www.wikidata.org/entity/Q36856671

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Proceedings of the National Academy of Sciences of the United States of America

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Akira Ito

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Birgitta Wiehager

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Camilla A Hansson Petersen

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Elzbieta Glaser

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Homira Behbahani

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Irina Alafuzoff

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Maria Ankarcrona

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Nyosha Alikhani

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Pavel F Pavlov

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Ville Leinonen

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P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP

Amyloid plaque core protein in Alzheimer disease and Down syndrome

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Translocation of proteins into mitochondria

Cytochrome c oxidase in Alzheimer's disease brain: purification and characterization.

Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD.

Analysis of single Alzheimer solid plaque cores by laser capture microscopy and nanoelectrospray/tandem mass spectrometry.

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity.

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