Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate. - Wikidata - awgldk - TriplyDB

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.

http://www.wikidata.org/entity/Q36858525

about

V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45.A common genetic variant in the 3'-UTR of vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA motif to alter chromogranin A processing and hypertension risk Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function Renin, (pro)renin and receptor: an update.V-ATPase-mediated granular acidification is regulated by the V-ATPase accessory subunit Ac45 in POMC-producing cells Adventures with insulin in the islets of Langerhans The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis.Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.Loss of endothelial furin leads to cardiac malformation and early postnatal death.Identification of domains within the V-ATPase accessory subunit Ac45 involved in V-ATPase transport and Ca2+-dependent exocytosis.Generation and characterization of non-competitive furin-inhibiting nanobodies.ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation.Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.HID-1 is required for homotypic fusion of immature secretory granules during maturation.Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks.A furin inhibitor downregulates osteosarcoma cell migration by downregulating the expression levels of MT1-MMP via the Wnt signaling pathway.Current knowledge of (pro)renin receptor as an accessory protein of vacuolar H+-ATPase.Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice.Optimization of Substrate-Analogue Furin Inhibitors.Proprotein convertase furin regulates osteocalcin and bone endocrine function.

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P2860

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.

http://www.wikidata.org/entity/Q36858525

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Role of furin in granular acid ...... Ac45 as a candidate substrate.

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type

label

Role of furin in granular acid ...... Ac45 as a candidate substrate.

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prefLabel

Role of furin in granular acid ...... Ac45 as a candidate substrate.

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PNAS.0800340105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Role of furin in granular acid ...... Ac45 as a candidate substrate.

@en

P2093

Anton J M Roebroek

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Daisy Flamez

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Els Louagie

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John W M Creemers

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Neil A Taylor

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Nicholas A Bright

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Pedro L Herrera

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Roel Quintens

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Sandra Meulemans

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Wim J M Van de Ven

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P2860

Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice

Precursor convertases in the secretory pathway, cytosol and extracellular milieu

Neuroendocrine secretory protein 7B2: structure, expression and functions

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice.

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

Binding of BiP to the processing enzyme lymphoma proprotein convertase prevents aggregation, but slows down maturation

Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell

Precursor processing by kex2/furin proteases

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

P304

12319-12324

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scholarly article

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10.1073/PNAS.0800340105

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34

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105

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23181117

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18713856

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Aizkuņģa dziedzeris

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2527909

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