Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma - Wikidata - awgldk - TriplyDB

Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

http://www.wikidata.org/entity/Q36858644

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The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanol Using glutamate homeostasis as a target for treating addictive disorders Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad RGS14 at the interface of hippocampal signaling and synaptic plasticity Differential response of glial fibrillary acidic protein-positive astrocytes in the rat prefrontal cortex following ethanol self-administration Conserved role of unc-79 in ethanol responses in lightweight mutant mice Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later Striatal signal transduction and drug addiction Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence.Reinstated ethanol-seeking in rats is modulated by environmental context and requires the nucleus accumbens core An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy.Identification of a deubiquitinating enzyme as a novel AGS3-interacting protein Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors.Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable.Amphetamine up-regulates activator of G-protein signaling 1 mRNA and protein levels in rat frontal cortex: the role of dopamine and glucocorticoid receptors.Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse.Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai.Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.G-protein βγ subunit dimers modulate kidney repair after ischemia-reperfusion injury in rats.Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.Activators of G-protein signaling 3: a drug addiction molecular gateway.Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence Motivation for alcohol becomes resistant to quinine adulteration after 3 to 4 months of intermittent alcohol self-administration Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction.New medications for drug addiction hiding in glutamatergic neuroplasticity.Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gαi G-Protein Regulatory Motif Complex.Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior.G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.The endocannabinoid 2-arachidonoylglycerol mediates D1 and D2 receptor cooperative enhancement of rat nucleus accumbens core neuron firing.Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection.Signals from the Fourth Dimension Regulate Drug Relapse The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol.Modeling relapse in animals.

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P2860

Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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2008 nî lūn-bûn

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2008年論文

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name

Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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Proceedings of the National Academy of Sciences of the United States of America

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Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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P2093

Anitra M Guillory

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Antonello Bonci

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F Woodward Hopf

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Ivan Diamond

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Jonathan K Chou

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Shao-Ju Chang

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P2860

Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits

Opiate-dependent modulation of adenylate cyclase

Receptor-independent activators of heterotrimeric G-protein signaling pathways

betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption

The neural basis of drug craving: an incentive-sensitization theory of addiction

G proteins: transducers of receptor-generated signals

The neural basis of addiction: a pathology of motivation and choice

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking.

Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.

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10.1073/PNAS.0706999105

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34

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105

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Patricia H Janak

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23186171

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18719114

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nucleus accumbens

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2527946

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