Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol.
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How addictive drugs disrupt presynaptic dopamine neurotransmissionChronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapseP2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disordersMutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibitionThe role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progressEthanol is self-administered into the nucleus accumbens shell, but not the core: evidence of genetic sensitivityMolecular targets and mechanisms for ethanol action in glycine receptorsAlcohol selectivity of β3-containing GABAA receptors: evidence for a unique extracellular alcohol/imidazobenzodiazepine Ro15-4513 binding site at the α+β- subunit interface in αβ3δ GABAA receptors.Intra-nucleus accumbens shell injections of R(+)- and S(-)-baclofen bidirectionally alter binge-like ethanol, but not saccharin, intake in C57Bl/6J mice.Plasticity of GABA(A) receptor-mediated neurotransmission in the nucleus accumbens of alcohol-dependent rats.GABAA receptor subtype involvement in addictive behaviour.Extrasynaptic delta-containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake.Extrasynaptic GABAA receptors in the nucleus accumbens are necessary for alcohol drinking.Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol.Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in miceMechanisms of Neuroplasticity and Ethanol's Effects on Plasticity in the Striatum and Bed Nucleus of the Stria Terminalis.Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease.Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens.A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors.Effects of exposure to moderate levels of ethanol during prenatal brain development on dendritic length, branching, and spine density in the nucleus accumbens and dorsal striatum of adult ratsEffect of ganaxolone and THIP on operant and limited-access ethanol self-administration.Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons.Gene Expression Under the Influence: Transcriptional Profiling of Ethanol in the BrainAssessing the genetic risk for alcohol use disordersAutosomal linkage scan for loci predisposing to comorbid dependence on multiple substances.Genes and Alcohol Consumption: Studies with Mutant Mice.The Potent Effect of Environmental Context on Relapse to Alcohol-Seeking After Extinction.Alcohol dependence: molecular and behavioral evidence.Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcoholRole of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent modelDynamic Adaptation in Neurosteroid Networks in Response to Alcohol.GABA type a receptor trafficking and the architecture of synaptic inhibition.Blockade of GABA(A) receptors in the paraventricular nucleus of the hypothalamus attenuates voluntary ethanol intake and activates the hypothalamic-pituitary-adrenocortical axis.Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats.Involvement of the GABAA Receptor in Age-Dependent Differences in Binge-Like Ethanol Intake.An Emerging Circuit Pharmacology of GABA Receptors
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Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@en
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@nl
type
label
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@en
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@nl
prefLabel
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@en
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@nl
P2093
P2860
P1476
Alpha4-containing GABAA recept ...... te moderate intake of alcohol.
@en
P2093
Dao-Yao He
Mridula Rewal
Rachel Jurd
T Michael Gill
P2860
P304
P356
10.1523/JNEUROSCI.3199-08.2009
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P577
2009-01-01T00:00:00Z