The molecular makeup and function of regulatory and effector synapses.
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Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsSpatiotemporal activation of Rac1 for engulfment of apoptotic cellsEctopic T-bet expression licenses dendritic cells for IL-12-independent priming of type 1 T cells in vitro.Multimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clustersCD80 and CD86 differentially regulate mechanical interactions of T-cells with antigen-presenting dendritic cells and B-cells.Transiently reduced PI3K/Akt activity drives the development of regulatory function in antigen-stimulated Naïve T-cells.Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones.Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity.A B-1a cell subset induces Foxp3(-) T cells with regulatory activity through an IL-10-independent pathway.Anti-LFA-1 antibodies enhance metastasis of ocular lymphoma to the brain and contralateral eye.AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling.Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice.Signal initiation in T-cell receptor microclusters.Sustained LFA-1 cluster formation in the immune synapse requires the combined activities of L-plastin and calmodulin.Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection.The adapter protein ADAP is required for selected dendritic cell functions.The bullseye synapse formed between CD4+ T-cell and staphylococcal enterotoxin B-pulsed dendritic cell is a suppressive synapse in T-cell response.The pro-oxidative drug WF-10 inhibits serial killing by primary human cytotoxic T-cells.Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering.Expression of SKAP-HOM in DCs is required for an optimal immune response in vivo.
P2860
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P2860
The molecular makeup and function of regulatory and effector synapses.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The molecular makeup and function of regulatory and effector synapses.
@en
type
label
The molecular makeup and function of regulatory and effector synapses.
@en
prefLabel
The molecular makeup and function of regulatory and effector synapses.
@en
P2093
P2860
P1476
The molecular makeup and function of regulatory and effector synapses.
@en
P2093
Bastian Dornbach
Matthias Gunzer
Peter Reichardt
P2860
P304
P356
10.1111/J.1600-065X.2007.00526.X
P577
2007-08-01T00:00:00Z