Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors.
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Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of InsulinInsights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S1' Loop Canonical ConformationSimple Pseudo-dipeptides with a P2' Glutamate: A NOVEL INHIBITOR FAMILY OF MATRIX METALLOPROTEASES AND OTHER METZINCINSSelective class IIa histone deacetylase inhibition via a nonchelating zinc-binding groupBiochemical and spectroscopic characterization of the catalytic domain of MMP16 (cdMMP16)Identification of novel drugs to target dormant micrometastasesInsights into the complex formed by matrix metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculationsAn integrated computational approach to rationalize the activity of non-zinc-binding MMP-2 inhibitorsKinetic and binding effects in peptide substrate selectivity of matrix metalloproteinase-2: Molecular dynamics and QM/MM calculations.Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer.Investigating chelating sulfonamides and their use in metalloproteinase inhibitorsScutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.Expression of matrix metalloproteinase-12 in aortic dissectionCytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding.Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease.Inhibition of Matrix Metalloproteinase 9 Enhances Rod Survival in the S334ter-line3 Retinitis Pigmentosa Model.Matrix metalloproteinases as potential targets in the venous dilation associated with varicose veins.Host-response therapeutics for periodontal diseasesIncorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity.Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.Microenvironment and tumor progression of melanoma: new therapeutic prospectives.Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects.3-Hydroxypyridinone derivatives as metal-sequestering agents for therapeutic use.The Inhibitory Effect of C-phycocyanin Containing Protein Extract (C-PC Extract) on Human Matrix Metalloproteinases (MMP-2 and MMP-9) in Hepatocellular Cancer Cell Line (HepG2).Testis peritubular myoid cells increase their motility and express matrix-metalloproteinase 9 (MMP-9) after interaction with embryonal carcinoma cells.Are matrix metalloproteinases relevant therapeutic targets for prostate cancer bone metastasis?Probing the S1' site for the identification of non-zinc-binding MMP-2 inhibitors.Structural and dynamics analysis of matrix metalloproteinases MMP-2 complexed with chemically modified tetracyclines (CMTs).Evidence for a role of matrix metalloproteinases and their inhibitors in primordial germ cell migration.Inhibition of MMP-9 activity following hypoxic ischemia in the developing brain using a highly specific inhibitor.Fell-Muir Lecture: Metalloproteinases: from demolition squad to master regulators.Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders.Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging.The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.Targeting the MMP-14/MMP-2/integrin αβ axis with multispecific N-TIMP2-based antagonists for cancer therapy
P2860
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P2860
Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Matrix metalloproteinase inhib ...... ost broad-spectrum inhibitors.
@en
type
label
Matrix metalloproteinase inhib ...... ost broad-spectrum inhibitors.
@en
prefLabel
Matrix metalloproteinase inhib ...... ost broad-spectrum inhibitors.
@en
P50
P1476
Matrix metalloproteinase inhib ...... ost broad-spectrum inhibitors.
@en
P304
P356
10.2174/138161207781039706
P577
2007-01-01T00:00:00Z