Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists.
about
Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cellsDiscovery of Compound A--a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activityGenomic and non-genomic effects of glucocorticoids: implications for breast cancerDeciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid ReceptorsDevelopment of macromolecular prodrug for rheumatoid arthritisIntergenerational Transmission of Stress in HumansSelective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitroVBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in miceBiology and pathobiology of lipid droplets and their potential role in the protection of the organ of Corti.The role of glucocorticoids for spiral ganglion neuron survival.Infection risk in patients on multiple sclerosis therapeutics.Investigation on critical structural motifs of ligands for triggering glucocorticoid receptor nuclear migration through molecular docking simulations.Minireview: latest perspectives on antiinflammatory actions of glucocorticoids.Extracellular matrix molecules: potential targets in pharmacotherapy.Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity.Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1.Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.Prednisolone induces apoptosis in corneal epithelial cells through the intrinsic pathwayA theoretical framework for gene induction and experimental comparisons.Differentiation and glucocorticoid regulated apopto-phagocytic gene expression patterns in human macrophages. Role of Mertk in enhanced phagocytosis.Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated.Rapid elevation of calcium concentration in cultured dorsal spinal cord astrocytes by corticosterone.Glucocorticoid-targeted therapies for the treatment of rheumatoid arthritis.Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic responseWnt-4 protects thymic epithelial cells against dexamethasone-induced senescence.Conserved steroid hormone homology converges on nuclear factor κB to modulate inflammation in asthma.Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UVAdministration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissuesDexamethasone Induces FcγRIIb Expression in RBL-2H3 CellsPsychological stress and aging: role of glucocorticoids (GCs)Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivoRole of the hypothalamic-pituitary-adrenal axis in developmental programming of health and disease.An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel diseaseBrain-specific homeobox factor as a target selector for glucocorticoid receptor in energy balance.Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis.Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells.Modulation of transcription parameters in glucocorticoid receptor-mediated repression.Role of dual specificity phosphatases in biological responses to glucocorticoids.
P2860
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P2860
Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Molecular mechanisms of glucoc ...... cocorticoid receptor agonists.
@en
type
label
Molecular mechanisms of glucoc ...... cocorticoid receptor agonists.
@en
prefLabel
Molecular mechanisms of glucoc ...... cocorticoid receptor agonists.
@en
P2093
P1476
Molecular mechanisms of glucoc ...... cocorticoid receptor agonists.
@en
P2093
Cindy Stahn
Daniel W Hommes
Mark Löwenberg
P356
10.1016/J.MCE.2007.05.019
P577
2007-06-02T00:00:00Z