Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases.
about
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgarisInter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosisProteolysis of the docking protein HEF1 and implications for focal adhesion dynamicsThe fate of desmosomal proteins in apoptotic cellsArsenic Exposure Increases Monocyte Adhesion to the Vascular Endothelium, a Pro-Atherogenic MechanismCdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activationStrain-dependent induction of enterocyte apoptosis by Giardia lamblia disrupts epithelial barrier function in a caspase-3-dependent manner.Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/ConneMultiple roles of matrix metalloproteinases during apoptosis.Stretch and Shear Interactions Affect Intercellular Junction Protein Expression and Turnover in Endothelial Cells.Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells.Cyclosporine A--protection against microvascular hyperpermeability is calcineurin independent.Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCATMMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis.Apoptosis in the vasculature: mechanisms and functional importance.Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosisMatrix metalloproteinases and gastrointestinal cancers: Impacts of dietary antioxidants.Morphologic responses of endothelium to shear stress: reorganization of the adherens junction.Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis.Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.Disruption of the endothelial barrier by proteases from the bacterial pathogen Pseudomonas aeruginosa: implication of matrilysis and receptor cleavageNon-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death.Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.Potential role for ADAM15 in pathological neovascularization in mice.P2Y2 receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells.N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis?Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin TraffickingActive participation of endothelial cells in inflammation.Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase.Molecular and cellular mechanisms of ectodomain sheddingAntagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathway.Endothelial tyrosine kinase receptor B prevents VE-cadherin cleavage and protects against atherosclerotic lesion development in ApoE-/- mice.Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta.Inherent phenotypic plasticity facilitates progression of head and neck cancer: endotheliod characteristics enable angiogenesis and invasionGalectin-3 cleavage: a novel surrogate marker for matrix metalloproteinase activity in growing breast cancers.A peptide inhibitor of the urokinase/urokinase receptor system inhibits alteration of the blood-retinal barrier in diabetes.Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow
P2860
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P2860
Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Cleavage of beta-catenin and p ...... spases and metalloproteinases.
@en
type
label
Cleavage of beta-catenin and p ...... spases and metalloproteinases.
@en
prefLabel
Cleavage of beta-catenin and p ...... spases and metalloproteinases.
@en
P2093
P2860
P356
P1476
Cleavage of beta-catenin and p ...... spases and metalloproteinases.
@en
P2093
P2860
P304
P356
10.1091/MBC.9.6.1589
P577
1998-06-01T00:00:00Z