Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes.
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SXR, a novel steroid and xenobiotic-sensing nuclear receptorEnvironmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response elementA reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitroRegulation of cytochrome P450 (CYP) genes by nuclear receptors.The human CYP3A subfamily: practical considerations.Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes.PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor.Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.Membrane-bound and exosomal metastasis-associated C4.4A promotes migration by associating with the α(6)β(4) integrin and MT1-MMP.CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene.Xenobiotic-inducible transcription of cytochrome P450 genes.Zonation of hepatic cytochrome P-450 expression and regulation.Nuclear receptor involvement in the regulation of rat cytochrome P450 3A23 expression.Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway.Scaffold-Based microRNA Therapies in Regenerative Medicine and Cancer.New nucleotide sequence data on the EMBL File ServerIn vitro 3-D culture demonstrates incompetence in improving maintenance ability of primary hepatocytes
P2860
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P2860
Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Paradoxical transcriptional ac ...... ures of adult rat hepatocytes.
@en
type
label
Paradoxical transcriptional ac ...... ures of adult rat hepatocytes.
@en
prefLabel
Paradoxical transcriptional ac ...... ures of adult rat hepatocytes.
@en
P2093
P2860
P356
P1476
Paradoxical transcriptional ac ...... ures of adult rat hepatocytes.
@en
P2093
E G Schuetz
H J Burger
J D Schuetz
P S Guzelian
P2860
P304
P356
10.1073/PNAS.89.6.2145
P407
P577
1992-03-01T00:00:00Z